Cárdenas Yolitzy, Ríos-Silva Mónica, Huerta Miguel, López Marisa, Bricio-Barrios Jaime, Ortiz-Mesina Mónica, Urzúa Zorayda, Saavedra-Molina Alfredo, Trujillo Xóchitl
1 Dr. Enrico Stefani Research Unit, University Center for Biomedical Research, University of Colima, Colima, Mexico.
2 National Council of Science and Technology (CONACYT), University of Colima, Colima, Colima, Mexico.
J Med Food. 2019 May;22(5):538-541. doi: 10.1089/jmf.2018.0124. Epub 2019 Mar 12.
Nopal is used in Mexico as both food and traditional medicine for metabolic diseases. Our aim was to analyze the effect of the chronic administration of mucilage fiber extracted from nopal (; 500 mg/kg body weight per day) on male Wistar rats on a high-fructose diet (HFD). After which three groups were administered one of the following for 30 days: whole-fresh nopal mixed in water, mucilage, and control. Metabolic and hemodynamic parameters (triglycerides, cholesterol, fasting glucose, oral glucose tolerance test, blood pressure, and abdominal circumference) were determined. Rats administered nopal and mucilage had lower levels of triglycerides and diastolic arterial pressure than control, but only nopal had significant differences. Furthermore, systolic and diastolic pressure were higher in the control group. Thus, whole nopal and mucilage improve metabolic parameters in rats fed a HFD.
在墨西哥，仙人掌被用作食物和治疗代谢性疾病的传统药物。我们的目的是分析长期给予从仙人掌中提取的黏液纤维（每天500毫克/千克体重）对高果糖饮食（HFD）的雄性Wistar大鼠的影响。之后，将三组大鼠分别给予以下其中一种处理，持续30天：与水混合的新鲜仙人掌全株、黏液和对照组。测定了代谢和血流动力学参数（甘油三酯、胆固醇、空腹血糖、口服葡萄糖耐量试验、血压和腹围）。给予仙人掌和黏液的大鼠甘油三酯水平和舒张压低于对照组，但只有仙人掌组有显著差异。此外，对照组的收缩压和舒张压更高。因此，仙人掌全株和黏液可改善高果糖饮食喂养大鼠的代谢参数。
