Gulstad Mikkel Bak, Thomsen Henrik
Lindesnæsvej 1, 8200 Aarhus N.
Ugeskr Laeger. 2015 Jan 26;177(2A):84-5.
Ischaemic colitis is a potentially mortal illness which usually arises from decreased mesenteric blood flow. Loperamide is used in the treatment of both acute and chronic diarrhoea. We present a case of a 62-year-old man with no history of abdominal illness who was admitted with a distended and sore abdomen. Ten days prior to admission he was treated with loperamide. Because of his severe condition he had an emergency laparotomy which showed a necrotic colon and terminal ileum - both were resected. No thromboembolic cause was found and we therefore suggest loperamide as an inducing factor.
缺血性结肠炎是一种可能致命的疾病,通常由肠系膜血流减少引起。洛哌丁胺用于治疗急性和慢性腹泻。我们报告一例62岁男性患者,他无腹部疾病史,因腹部肿胀和疼痛入院。入院前10天,他接受了洛哌丁胺治疗。由于病情严重,他接受了急诊剖腹手术,术中发现结肠和回肠末端坏死,均被切除。未发现血栓栓塞原因,因此我们认为洛哌丁胺是诱发因素。