Gasbarrini G, Corazza G R, Feliciani M, Albano O, Stufano N, Altomare E, Fontana G, Valpiani D, Chiodo F, Banterle C
Arzneimittelforschung. 1986 Dec;36(12):1843-5.
The efficacy of 1-(2,6-dimethylphenyl)-3-methyl-amidinourea hydrochloride (lidamidine HCl, WHR-1142 A) an aryl-substituted amidinourea recently synthesized, was compared with that of loperamide in 32 patients with acute diarrhoea. The results of the study show that lidamidine HCl and loperamide had comparable effects in the pharmacological treatment of acute non-specific diarrhoea. Lidamidine HCl was also shown to be well tolerated; side-effects were generally minor and self-limiting.
1-(2,6-二甲基苯基)-3-甲基脒基脲盐酸盐（利达脒盐酸盐，WHR-1142 A）是一种最近合成的芳基取代脒基脲，对32例急性腹泻患者比较了其与洛哌丁胺的疗效。研究结果表明，利达脒盐酸盐和洛哌丁胺在急性非特异性腹泻的药物治疗中具有相当的效果。利达脒盐酸盐耐受性也良好；副作用一般较小且为自限性。
