Urso C, Messerini L, de Meester W, Ferri G
Pathologica. 1989 Nov-Dec;81(1076):611-6.
Two rare cases of laryngeal paraganglioma are reported. The first patient was a 14-year-old girl, that had a new laterocervical paraganglioma, 4 years after the excision of a laryngeal tumor. The other patient was a 33-year-old man. In both the cases, the diagnosis was made on histopathological ground and the tumors displayed the typical histological pattern of paragangliomas: epithelioid tumor cell arranged in nests (Zell-ballen) in a vascular stroma. Neoplastic cells were found to contain argyrophil granules and chromogranin. Laryngeal paragangliomas reported in the literature are 73, they generally are supraglottic, show no sex predilection and prefer the V-VII decades of age.
报告了两例罕见的喉副神经节瘤病例。首例患者为一名14岁女孩,在喉部肿瘤切除4年后出现了新的颈侧副神经节瘤。另一例患者是一名33岁男性。在这两例病例中,诊断均基于组织病理学依据,肿瘤表现出副神经节瘤典型的组织学模式:上皮样肿瘤细胞在血管基质中呈巢状排列(Zell-ballen)。发现肿瘤细胞含有嗜银颗粒和嗜铬粒蛋白。文献中报道的喉副神经节瘤有73例,它们通常位于声门上区,无性别倾向,好发于50-70岁。