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猪脊柱锥形束计算机断层扫描和磁共振成像的验证:与多探测器计算机断层扫描及解剖标本的对比研究

Validation of cone-beam computed tomography and magnetic resonance imaging of the porcine spine: a comparative study with multidetector computed tomography and anatomical specimens.

作者信息

de Freitas Ricardo Miguel Costa, Andrade Celi Santos, Caldas José Guilherme Mendes Pereira, Kanas Alexandre Fligelman, Cabral Richard Halti, Tsunemi Miriam Harumi, Rodríguez Hernán Joel Cervantes, Rabbani Said Rahnamaye

机构信息

Radiology Department, Instituto de Radiologia-InRad, Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, s/n(o) - Rua 1 - Cerqueira César, CEP: 05403-900, São Paulo, SP, Brazil; Radiology Unit, Instituto do Câncer do Estado de São Paulo-ICESP, Avenida Doutor Arnaldo, 251, Cerqueira César, 01246-000, São Paulo, SP, Brazil.

Radiology Department, Instituto de Radiologia-InRad, Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, s/n(o) - Rua 1 - Cerqueira César, CEP: 05403-900, São Paulo, SP, Brazil.

出版信息

Spine J. 2015 May 1;15(5):992-9. doi: 10.1016/j.spinee.2015.01.017. Epub 2015 Jan 19.

DOI:10.1016/j.spinee.2015.01.017
PMID:25614150
Abstract

BACKGROUND CONTEXT

New spinal interventions or implants have been tested on ex vivo or in vivo porcine spines, as they are readily available and have been accepted as a comparable model to human cadaver spines. Imaging-guided interventional procedures of the spine are mostly based on fluoroscopy or, still, on multidetector computed tomography (MDCT). Cone-beam computed tomography (CBCT) and magnetic resonance imaging (MRI) are also available methods to guide interventional procedures. Although some MDCT data from porcine spines are available in the literature, validation of the measurements on CBCT and MRI is lacking.

PURPOSE

To describe and compare the anatomical measurements accomplished with MDCT, CBCT, and MRI of lumbar porcine spines to determine if CBCT and MRI are also useful methods for experimental studies.

STUDY DESIGN

An experimental descriptive-comparative study.

METHODS

Sixteen anatomical measurements of an individual vertebra from six lumbar porcine spines (n=36 vertebrae) were compared with their MDCT, CBCT, and MRI equivalents. Comparisons were made for the absolute values of the parameters.

RESULTS

Similarities were found in all imaging methods. Significant correlation (p<.05) was observed with all variables except those that included cartilaginous tissue from the end plates when the anatomical study was compared with the imaging methods.

CONCLUSIONS

The CBCT and MRI provided imaging measurements of the lumbar porcine spines that were similar to the anatomical and MDCT data, and they can be useful for specific experimental research studies.

摘要

背景

新的脊柱干预措施或植入物已在离体或活体猪脊柱上进行测试,因为猪脊柱容易获得,并且已被公认为与人类尸体脊柱相当的模型。脊柱的影像引导介入手术大多基于荧光透视法,或者仍然基于多探测器计算机断层扫描(MDCT)。锥束计算机断层扫描(CBCT)和磁共振成像(MRI)也是引导介入手术的可用方法。尽管文献中有一些来自猪脊柱的MDCT数据,但缺乏对CBCT和MRI测量的验证。

目的

描述和比较用MDCT、CBCT和MRI对猪腰椎进行的解剖学测量,以确定CBCT和MRI是否也是实验研究的有用方法。

研究设计

一项实验性描述性比较研究。

方法

对来自六头猪腰椎(n = 36个椎体)的单个椎体的16项解剖学测量结果与其MDCT、CBCT和MRI对应结果进行比较。对参数的绝对值进行比较。

结果

在所有成像方法中均发现了相似性。当将解剖学研究与成像方法进行比较时,除了那些包括终板软骨组织的变量外,所有变量均观察到显著相关性(p <.05)。

结论

CBCT和MRI提供的猪腰椎成像测量结果与解剖学和MDCT数据相似,它们可用于特定的实验研究。

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