Grossi A, Barbetti F, Bulletta C, Ciampalini P, Jaffrain-Rea M L, Tamburrano G
Minerva Endocrinol. 1989 Oct-Dec;14(4):213-9.
Fourteen patients with pituitary lesions and 6 normal subjects underwent the following tests: a) LHRH (100 mcg) + TRH (200 mcg) + Human Insulin (0.1 UI/kg) i.v. (Politest "A"); b) LHRH (100 mcg) + TRH (200 mcg) + GHRH 1-29NH2 (100 mcg) i.v. (Politest "B"); c) GHRH 1-29NH2 (100 mcg) i.v. (GHRH-TEST). FSH, LH and PRL, as assayed in patients and controls in response to Politest "A" and "B", revealed no significant differences between the tests. Plasma TSH values were significantly higher after Politest "B" in both patients and normals. The GH response after Politest "A" and "B" was similar in magnitude and concordant in 88.8% of cases.
14例垂体病变患者和6名正常受试者接受了以下检查：a）静脉注射促性腺激素释放激素（LHRH，100微克）+促甲状腺激素释放激素（TRH，200微克）+人胰岛素（0.1国际单位/千克）（复合试验“A”）；b）静脉注射促性腺激素释放激素（LHRH，100微克）+促甲状腺激素释放激素（TRH，200微克）+生长激素释放激素1-29NH2（100微克）（复合试验“B”）；c）静脉注射生长激素释放激素1-29NH2（100微克）（生长激素释放激素试验）。对患者和对照组进行复合试验“A”和“B”检测后，促卵泡生成素（FSH）、促黄体生成素（LH）和催乳素（PRL）的检测结果显示，各项检查之间无显著差异。患者和正常人在复合试验“B”后血浆促甲状腺激素（TSH）值均显著升高。复合试验“A”和“B”后的生长激素（GH）反应在幅度上相似，88.8%的病例反应一致。
