Johnson-Warrington Vicki, Sewell Louise, Morgan Mike, Singh Sally
University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Respirology. 2015 Apr;20(3):434-8. doi: 10.1111/resp.12469. Epub 2015 Jan 23.
Patients with interstitial lung disease (ILD) are increasingly being referred to pulmonary rehabilitation (PR) where exercise capacity is measured, often by an incremental shuttle walk test (ISWT). These patients are frequently limited by severe dyspnoea and exertional desaturation. Available guidelines suggest two ISWT are needed; however, this is time consuming and it has not been reported whether a practice ISWT is necessary in ILD. We aimed to investigate if a practice ISWT is needed for patients with ILD referred to PR.
Patients with ILD who attended a PR assessment performed two ISWT as per standard protocol. Hospital notes were retrieved and relevant data extracted and validated. Endurance shuttle walk test (ESWT) level was calculated at 85% VO2 peak as estimated from the first ISWT (ISWT 1) and second ISWT (ISWT 2).
Forty-three patients were included (18 with idiopathic pulmonary fibrosis). There was a mean change of 28.84 (31.71) m between the two ISWT (P < 0.001) with 72.1% of patients walking further on ISWT 2. A Bland-Altman plot showed good agreement between the ISWTs; however, the limits of agreement were wide. There was a significant difference in ESWT levels (P < 0.001) when calculated from ISWT 1 and ISWT 2. ISWT 1 distance, post-ISWT 1 heart rate and baseline Borg breathlessness score were significant variables (P < 0.05) in linear regression, but this only explained 42.6% of the variance (R(2) 0.426).
A practice ISWT is necessary to accurately assess exercise capacity. It was not possible to predict which patients did not need to complete two ISWT.
间质性肺疾病(ILD)患者越来越多地被转诊至肺康复(PR)机构,在那里通常通过递增式往返步行试验(ISWT)来测量运动能力。这些患者常因严重呼吸困难和运动性低氧血症而受限。现有指南建议需要进行两次ISWT;然而,这很耗时,且尚未有关于ILD患者是否需要进行预试验性ISWT的报道。我们旨在调查转诊至PR的ILD患者是否需要进行预试验性ISWT。
参加PR评估的ILD患者按照标准方案进行两次ISWT。检索医院病历并提取和验证相关数据。根据第一次ISWT(ISWT 1)和第二次ISWT(ISWT 2)估算出的85%最大摄氧量(VO2峰值)计算耐力往返步行试验(ESWT)水平。
纳入43例患者(18例特发性肺纤维化患者)。两次ISWT之间的平均变化为28.84(31.71)米(P < 0.001),72.1%的患者在ISWT 2中行走距离更远。Bland-Altman图显示两次ISWT之间一致性良好;然而,一致性界限较宽。根据ISWT 1和ISWT 2计算的ESWT水平存在显著差异(P < 0.001)。ISWT 1距离、ISWT 1后心率和基线Borg呼吸困难评分在线性回归中是显著变量(P < 0.05),但这仅解释了42.6%的方差(决定系数R²为0.426)。
进行预试验性ISWT对于准确评估运动能力是必要的。无法预测哪些患者无需完成两次ISWT。