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[乳腺导管癌。电子显微镜研究]

[Ductal carcinoma of the breast. Electron microscopic study].

作者信息

Mroczka B, Domaniewski J

出版信息

Patol Pol. 1989;40(2):171-9.

PMID:2561607
Abstract

Electron microscopic study of the breast tumors were carried out on 67 patients. There were 7 intraductal carcinomas and 60 infiltrating ductal carcinomas of the breast. Observations were made on the morphological characteristics of neoplastic cells, myoepithelial cells and basal lamina. Cells organelles in the neoplastic cells are similar in both types of ductal carcinomas. Nuclei are predominantly large and irregular with poor dense chromatin. Often a lot of filaments are around the nuclei. Myoepithelial cells in the infiltrating ductal carcinomas are ultrastructurally the same as seen in the intraductal carcinomas, but they seems to be less numerously than in the intraductal carcinomas. In the intraductal carcinomas of the breast basal lamina is irregular and from time to time is disrupt. In the infiltrating ductal carcinomas basal lamina is usually absent, but sometimes we can find its short fragments.

摘要

对67例乳腺肿瘤患者进行了电子显微镜研究。其中有7例乳腺导管内癌和60例浸润性导管癌。对肿瘤细胞、肌上皮细胞和基底膜的形态特征进行了观察。两种类型的导管癌中肿瘤细胞的细胞器相似。细胞核大多大且不规则,染色质致密性差。细胞核周围常常有许多细丝。浸润性导管癌中的肌上皮细胞在超微结构上与导管内癌所见相同,但数量似乎比导管内癌少。乳腺导管内癌的基底膜不规则,且时有中断。浸润性导管癌中通常没有基底膜,但有时可以发现其短片段。

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