[Immunocytochemical demonstration of S-100 protein in adenoid cystic carcinoma of the salivary gland].

Immunocytochemical study was performed for the presence of S-100 protein in adenoid cystic carcinoma (ACC) of salivary gland and normal salivary gland tissues with the immunogold-silver staining method (IGSS). Myoepithelial cells, intercalated duct cells and serous acinar cells of normal salivary gland were S-100 positive. In ACC, S-100 protein can be found in component cells of various histological patterns of the tumor. The results suggest, according to the distribution patterns of S-100 protein positive cells in the tumor tissues, that ACC may originate partly from intercalated duct cells and partly from myoepithelial cells.