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[唾液腺腺样囊性癌中角蛋白的免疫组织化学研究]

[An immunohistochemical study of keratin in adenoid cystic carcinoma of the salivary gland].

作者信息

Wang F G

机构信息

Department of oral pathology, Anhui Medical University, Hefei.

出版信息

Zhonghua Kou Qiang Yi Xue Za Zhi. 1990 May;25(3):149-51, 190.

PMID:1698592
Abstract

An immunohistochemical study of keratin was performed in forty-five cases of adenoid cystic carcinoma of salivary gland, the results were as follows: keratin was distributed in the duct system of normal salivary gland, but the acini were negative. The distribution of keratin were varied in different patterns of adenoid cystic carcinoma. The amount of synthesis of keratin was many in tubular type of high differentiated carcinoma, but, in basaloid solid type of low differentiated carcinoma, the synthesis of keratin was less; the content of keratin in cribriform and trabecular type was between the tubular type and basaloid solid type, and the former had more keratin than the latter.

摘要

对45例涎腺腺样囊性癌进行了角蛋白的免疫组织化学研究,结果如下:角蛋白分布于正常涎腺的导管系统,但腺泡呈阴性。在不同类型的腺样囊性癌中,角蛋白的分布模式各异。高分化管状型癌中角蛋白的合成量较多,而低分化基底样实性型癌中角蛋白的合成量较少;筛状型和小梁型中的角蛋白含量介于管状型和基底样实性型之间,且前者的角蛋白含量多于后者。

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