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腹腔镜结直肠手术对老年患者有益吗?一项系统评价与荟萃分析。

Is laparoscopic colorectal surgery beneficial for elderly patients? A systematic review and meta-analysis.

作者信息

Seishima Ryo, Okabayashi Koji, Hasegawa Hirotoshi, Tsuruta Masashi, Shigeta Kohei, Matsui Shimpei, Yamada Toru, Kitagawa Yuko

机构信息

Department of Surgery, Keio University School of Medicine, 35 Shinano-machi, Shinjuku-ku, Tokyo, 1608582, Japan.

出版信息

J Gastrointest Surg. 2015 Apr;19(4):756-65. doi: 10.1007/s11605-015-2748-9. Epub 2015 Jan 24.

Abstract

BACKGROUND

Elderly patients who undergo major abdominal surgery are potentially at a higher risk of perioperative mortality and postoperative complications. Although laparoscopic surgery has been widely accepted as a less invasive surgical procedure for colorectal diseases, the benefits for elderly patients have not been validated.

AIM

To compare postoperative outcomes and long-term survival between laparoscopic and open colorectal surgery in the elderly population.

METHODS

A literature search was electronically performed to identify all studies comparing postoperative outcomes between laparoscopic and open colorectal resections in the elderly population. Primary outcomes were postoperative mortality and complications, and the secondary outcome was long-term survival.

RESULTS

Overall, 30 studies (70,946 patients) met our inclusion criteria. Laparoscopic surgery was significantly associated with a decreased risk of perioperative mortality [odds ratio (OR), 0.55; 95% confidence interval (CI), 0.45-0.68; P < 0.01] and postoperative complications (OR, 0.55; 95% CI, 0.48-0.63; P < 0.01) compared with open surgery. There was no significant difference in long-term survival between the two procedures (OR, 0.89; 95% CI, 0.72-1.07; P = 0.31).

CONCLUSIONS

Laparoscopic colorectal surgery in the elderly population has significant advantages in terms of short-term outcomes. Aggressive application of laparoscopic colorectal surgery should be considered for the elderly population.

摘要

背景

接受腹部大手术的老年患者围手术期死亡和术后并发症的风险可能更高。尽管腹腔镜手术已被广泛认为是一种用于结直肠疾病的侵入性较小的手术方法,但对老年患者的益处尚未得到证实。

目的

比较老年人群中腹腔镜与开放结直肠手术的术后结局和长期生存率。

方法

通过电子方式进行文献检索,以确定所有比较老年人群中腹腔镜与开放结直肠切除术术后结局的研究。主要结局为术后死亡率和并发症,次要结局为长期生存率。

结果

总体而言,30项研究(70946例患者)符合我们的纳入标准。与开放手术相比,腹腔镜手术与围手术期死亡风险降低显著相关[比值比(OR),0.55;95%置信区间(CI),0.45 - 0.68;P < 0.01]以及术后并发症风险降低显著相关(OR,0.55;95% CI,0.48 - 0.63;P < 0.01)。两种手术方法在长期生存率方面无显著差异(OR,0.89;95% CI,0.72 - 1.07;P = 0.31)。

结论

老年人群的腹腔镜结直肠手术在短期结局方面具有显著优势。对于老年人群应考虑积极应用腹腔镜结直肠手术。

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