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腹腔镜与开腹结直肠切除术治疗老年患者的效果比较。

Laparoscopic versus open colorectal resection in the elderly population.

机构信息

Academic Surgical Unit, St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.

出版信息

Surg Endosc. 2013 Jan;27(1):19-30. doi: 10.1007/s00464-012-2414-1. Epub 2012 Jun 30.

Abstract

BACKGROUND

Elderly patients are often regarded as high-risk patients for major abdominal surgery because of a lack of functional reserve and associated medical comorbidities. The aim of this systematic review and pooled analysis was to review the current data published regarding the differences in operative outcomes of laparoscopic and open surgery in the elderly population.

METHODS

A systematic literature search of Medline, Embase, Web of Science, and Cochrane databases was performed. Studies that compared outcome following laparoscopic and open colorectal resections in the elderly (≥70) population were included. Primary outcomes were operative death, anastomotic leak, pneumonia, length of hospital stay, and return to bowel function. Secondary outcomes were operative time, intraoperative blood loss, postoperative cardiac morbidity, ileus, and postoperative wound infection.

RESULTS

The results of this systematic review and pooled analysis demonstrate the safety and potential benefits of laparoscopic colorectal resection in the elderly population. The latter include reduction in length of hospital stay, intraoperative blood loss, incidence of postoperative pneumonia, time to return of normal bowel function, incidence of postoperative cardiac complications, and wound infections.

CONCLUSION

The results of this pooled analysis demonstrate the potential short-term advantages of laparoscopic colorectal resection in the elderly population. Further studies are required to examine the long-term survival following laparoscopic and open colorectal resections in the elderly population.

摘要

背景

由于功能储备不足和相关的合并症,老年患者常被视为大腹部手术的高危患者。本系统回顾和汇总分析的目的是回顾目前发表的关于老年人群中腹腔镜与开放手术手术结果差异的相关数据。

方法

对 Medline、Embase、Web of Science 和 Cochrane 数据库进行了系统的文献检索。纳入了比较腹腔镜和开放结直肠切除术在老年(≥70 岁)人群中手术结果的研究。主要结局是手术死亡、吻合口漏、肺炎、住院时间和恢复肠道功能。次要结局是手术时间、术中出血量、术后心脏发病率、肠梗阻和术后伤口感染。

结果

本系统回顾和汇总分析的结果表明腹腔镜结直肠切除术在老年人群中的安全性和潜在益处。后者包括住院时间、术中出血量、术后肺炎发生率、正常肠道功能恢复时间、术后心脏并发症发生率和伤口感染率的降低。

结论

本汇总分析的结果表明腹腔镜结直肠切除术在老年人群中具有潜在的短期优势。需要进一步的研究来检查老年人群中腹腔镜和开放结直肠切除术后的长期生存情况。

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