Geltzeiler Cristina B, Young J Isaac, Diggs Brian S, Keyashian Kian, Deveney Karen, Lu Kim C, Tsikitis V Liana, Herzig Daniel O
Department of Surgery, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Rd., Mail Code L223A, Portland, OR, 97239, USA,
J Gastrointest Surg. 2015 May;19(5):905-10. doi: 10.1007/s11605-015-2749-8. Epub 2015 Jan 24.
Strictureplasty is an alternative to resection for treatment of Crohn's disease (CD) strictures. It preserves bowel length, and specialized centers report favorable outcomes. Strictureplasty rates, however, are thought to be low, and it was recently removed from required cases for colon and rectal surgery residents. We examined operative characteristics, and trends in its use using a large national database.
We examined the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database from 2005 to 2012, identifying patients with CD who underwent strictureplasty. We identified patient characteristics, outcome variables, and trends in utilization of strictureplasty.
A total of 9172 patients underwent surgery for CD. Two hundred fifty-six (2.8 %) underwent strictureplasty. Median preoperative albumin was 3.6. Preoperative steroid use and weight loss rates were 39 and 8 %. Rates of wound infection and organ space infection were 11 and 4 %. Rate of reoperation was 6 %. Outcomes did not change significantly over time (all p = NS). The proportion of CD operations that included a strictureplasty decreased from 5.1 to 1.7 % (OR 0.902 with each additional year, 95 % CI (0.852, 0.960), p < 0.001).
Strictureplasty as treatment for CD is decreasing in the ACS-NSQIP database. Infectious complications and reoperation rates following strictureplasty are low and have not changed over time.
狭窄成形术是治疗克罗恩病(CD)狭窄的一种替代切除术的方法。它可保留肠管长度,专业中心报告其疗效良好。然而,狭窄成形术的实施率据认为较低,并且最近它已从结肠和直肠外科住院医师的必做病例中被剔除。我们使用一个大型国家数据库研究了其手术特征及使用趋势。
我们研究了美国外科医师学会国家外科质量改进计划(ACS-NSQIP)2005年至2012年的数据库,识别接受狭窄成形术的CD患者。我们确定了患者特征、结局变量以及狭窄成形术的使用趋势。
共有9172例患者接受了CD手术。256例(2.8%)接受了狭窄成形术。术前白蛋白中位数为3.6。术前使用类固醇和体重减轻率分别为39%和8%。伤口感染和器官腔隙感染率分别为11%和4%。再次手术率为6%。随着时间推移,结局无显著变化(所有p值均无统计学意义)。包含狭窄成形术的CD手术比例从5.1%降至1.7%(每增加一年,比值比为0.902,95%可信区间为(0.852, 0.960),p < 0.001)。
在ACS-NSQIP数据库中,作为CD治疗方法的狭窄成形术正在减少。狭窄成形术后的感染并发症和再次手术率较低,且未随时间变化。