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克罗恩病回结肠吻合口复发行狭窄成形术的长期结果

Long-term results of strictureplasty for ileocolonic anastomotic recurrence in Crohn's disease.

作者信息

Yamamoto T, Keighley M R

机构信息

University Department of Surgery, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK.

出版信息

J Gastrointest Surg. 1999 Sep-Oct;3(5):555-60. doi: 10.1016/s1091-255x(99)80112-7.

Abstract

This study examined the outcome of strictureplasty for recurrence at the ileocolonic anastomosis after resection (ileocolonic strictureplasty) in Crohn's disease. The records of 42 patients who underwent ileocolonic strictureplasty between 1980 and 1997 were reviewed. The method of ileocolonic strictureplasty was Heineke-Mikulicz reconstruction for a short stricture (</=6 cm) in 41 patients and Finney reconstruction for a long stricture (20 cm) in one. Synchronous operations were performed for coexisting small bowel Crohn's disease in 17 patients: strictureplasty in eight, resection in two, and both in seven. Postoperatively there were two intra-abdominal abscesses, which were treated conservatively. There were no deaths. All except two patients had complete relief of symptoms after operation. Most of the patients who had preoperative weight loss gained weight (median gain +2.6 kg). After a median follow-up of 99 months, 24 patients (57%) had a symptomatic recurrence. Three patients were successfully managed by medical treatment. The other 21 patients (50%) required surgery for recurrence (20 for recurrence at the previous ileocolonic strictureplasty site). At present, two patients are symptomatic and currently receiving corticosteroid therapy. All other patients have had no recurrent symptoms. None of the patients have developed short bowel syndrome or small bowel carcinoma. Strictureplasty is a safe and efficacious procedure for ileocolonic anastomotic recurrence in Crohn's disease.

摘要

本研究探讨了克罗恩病患者切除术后回结肠吻合口复发(回结肠狭窄成形术)行狭窄成形术的疗效。回顾了1980年至1997年间接受回结肠狭窄成形术的42例患者的病历。41例短狭窄(≤6 cm)患者采用海涅克-米库利兹重建术进行回结肠狭窄成形术,1例长狭窄(>20 cm)患者采用芬尼重建术。17例患者因并存小肠克罗恩病同期进行了手术:8例行狭窄成形术,2例行切除术,7例行两者联合手术。术后发生2例腹腔内脓肿,经保守治疗。无死亡病例。除2例患者外,所有患者术后症状均完全缓解。大多数术前体重减轻的患者体重增加(平均增加+2.6 kg)。中位随访99个月后,24例患者(57%)出现症状复发。3例患者经药物治疗成功控制。其他21例患者(50%)因复发需要手术治疗(20例在先前回结肠狭窄成形术部位复发)。目前,2例患者有症状,正在接受皮质类固醇治疗。所有其他患者均无复发症状。所有患者均未发生短肠综合征或小肠癌。狭窄成形术是治疗克罗恩病回结肠吻合口复发的一种安全有效的方法。

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