Kim C J, Cho J H, Chi J G
Department of Pathology, Seoul National University Children's Hospital, Korea.
J Korean Med Sci. 1989 Dec;4(4):159-62. doi: 10.3346/jkms.1989.4.4.159.
A case of aneurysmal ("angiomatoid") fibrous histiocytoma (AFH) in a 12-year-old girl is presented with its unusual clinicopathologic features. The lesion had the full microscopic characteristics of AFH described in prior reports, but it also had some features that differed from the original description of the disorder, such as the involvement of subcutis, its occurrence in the scalp, and a documented history of minor trauma. The lesion clinically resembled the gross features of hemangioma. The experience in the present case raises the need for considering AFH as one of major differential diagnosis of nodular cutaneous tumors in children that simulate malignancy such as angiomatoid malignant fibrous histiocytoma and Kaposi's sarcoma.
本文报告了一例12岁女孩的动脉瘤样(“血管样”)纤维组织细胞瘤(AFH),并阐述了其不寻常的临床病理特征。该病变具有先前报告中描述的AFH的完整微观特征,但也有一些与该疾病最初描述不同的特征,如累及皮下组织、发生于头皮以及有轻微创伤的记录史。该病变在临床上类似于血管瘤的大体特征。本病例的经验表明,对于儿童中模拟恶性肿瘤的结节性皮肤肿瘤,如血管样恶性纤维组织细胞瘤和卡波西肉瘤,有必要将AFH视为主要鉴别诊断之一。