Grossman L D, White R R, Arber D A
Department of Plastic Surgery, Scott & White Clinic and Memorial Hospital, Temple, TX 76508, USA.
Ann Plast Surg. 1996 Jun;36(6):649-51. doi: 10.1097/00000637-199606000-00016.
This article reports a case of angiomatoid fibrous histiocytoma (AFH), a rare fibrous tissue tumor with unique clinical characteristics. Formerly, this tumor was classified as angiomatoid malignant fibrous histiocytoma. First described in 1979, AFH was felt to be a variant of malignant fibrous histiocytoma (MFH). One dominant characteristic that differentiates this tumor from the remainder of MFH subtypes is that it most often presents in individuals younger than 20 years of age. The usual MFH occurs in the seventh decade of life. Because of its rarity, AFH has been difficult to classify and, during this current year, has been designated as a separate entity, rather than a subtype of MFH. Clinically, the tumor presents as a soft-tissue mass in the subcutis or deep dermal layers of the body, often presenting on the extremities or neck. Local recurrence has been reported, but mortality figures are very favorable and wide local removal is sufficient treatment.
本文报道了一例血管样纤维组织细胞瘤（AFH），这是一种具有独特临床特征的罕见纤维组织肿瘤。以前，该肿瘤被归类为血管样恶性纤维组织细胞瘤。AFH于1979年首次被描述，曾被认为是恶性纤维组织细胞瘤（MFH）的一种变体。该肿瘤与MFH其他亚型的一个主要区别特征是，它最常出现在20岁以下的个体中。普通的MFH多发生在70岁左右。由于其罕见性，AFH一直难以分类，在今年，它已被指定为一个独立的实体，而不是MFH的一个亚型。临床上，该肿瘤表现为身体皮下或真皮深层的软组织肿块，常出现在四肢或颈部。已有局部复发的报道，但死亡率非常低，广泛的局部切除是足够的治疗方法。
