Kaplan Alesia, Berntson Daniel G, Ferrieri Patricia
Department of Pathology and Laboratory Medicine, University of Minnesota, and
Department of Clinical and Anatomic Pathology, Fairview Southdale Hospital, Minneapolis, Minnesota.
Lab Med. 2015 Winter;46(1):69-73. doi: 10.1309/LMRH7HXD8TAT5FFK.
We report a case of localized pulmonary cryptococcal infection in a 28-year-old Caucasian woman who was 1 month postpartum at the time of her arrival at the hospital. The patient reported right-side chest pain; on further work up, she was found to have an incidental pulmonary lesion of the left lower lung lobe. Surgical pathology examination and microbiology studies revealed localized cryptococcal infection. Cases of cryptococcal pneumonia in pregnant women and in the postpartum period have been described in the literature. However, cryptococcal infections are usually associated with various immunocompromised states, including human immunodeficiency virus (HIV) infection. Because pregnancy is associated with physiological immunosuppression, cryptococcal pneumonia should be considered in pregnant women, or women in the postpartum period, who have respiratory symptoms.
我们报告一例28岁白种女性的局限性肺隐球菌感染病例,该患者入院时处于产后1个月。患者自述右侧胸痛;进一步检查发现其左下肺叶有一偶然发现的肺部病变。手术病理检查和微生物学研究显示为局限性隐球菌感染。文献中已描述了孕妇及产后时期的隐球菌肺炎病例。然而,隐球菌感染通常与包括人类免疫缺陷病毒(HIV)感染在内的各种免疫功能低下状态相关。由于妊娠与生理性免疫抑制有关,对于有呼吸道症状的孕妇或产后女性,应考虑隐球菌肺炎。