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精神病患者的自我污名化与药物依从性——横断面研究

Self-stigma and adherence to medication in patients with psychotic disorders--cross-sectional study.

作者信息

Vrbová Kristýna, Kamarádová Dana, Látalová Klára, Ocisková Marie, Praško Ján, Mainerová Barbora, Cinculová Andrea, Kubínek Radim, Ticháčková Anežka

机构信息

Department of Psychiatry, Faculty of Medicine and Dentistry, Palacky University Olomouc, and University Hospital Olomouc, Czech Republic.

出版信息

Neuro Endocrinol Lett. 2014;35(7):645-52.

Abstract

OBJECTIVE

Adherence to treatment of mental disorders is one of the key factors influencing its success and, secondarily, the patients' quality of life and social adaptation. The cross-sectional study of 90 outpatients diagnosed with psychotic disorders aimed at determining if there was a relationship between discontinuation of psychoactive drugs in the past, current adherence to treatment and self-stigma.

METHODS

The assessment was made with the objective and subjective Clinical Global Impression - Severity scale, Drug Attitude Inventory, Internalized Stigma of Mental Illness (ISMI) scale and demographic data. The questionnaires were filled out by 79 patients, of whom 5 handed in incomplete questionnaires. Complete sets of data were obtained from 74 patients.

RESULTS

The data analysis showed that the levels of self-stigma as assessed by the total ISMI scores was not statistically significantly correlated with most of the demographic factors (age, age of illness onset, gender, education, marital status, employment, duration of the illness, number of hospitalizations and antipsychotic dosage). However, there was a significant negative correlation with current adherence to treatment.

摘要

目的

坚持精神障碍治疗是影响治疗成功的关键因素之一,其次还会影响患者的生活质量和社会适应能力。这项针对90名被诊断患有精神障碍的门诊患者的横断面研究,旨在确定过去精神活性药物停药情况、当前治疗依从性和自我污名化之间是否存在关联。

方法

使用客观和主观的临床总体印象-严重程度量表、药物态度量表、精神疾病内化污名(ISMI)量表以及人口统计学数据进行评估。79名患者填写了问卷,其中5人提交的问卷不完整。从74名患者那里获得了完整的数据集。

结果

数据分析表明,通过ISMI总分评估的自我污名化水平与大多数人口统计学因素(年龄、发病年龄、性别、教育程度、婚姻状况、就业情况、病程、住院次数和抗精神病药物剂量)之间无统计学显著相关性。然而,与当前治疗依从性存在显著负相关。

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