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精神分裂症患者对药物治疗的负面态度的相关因素。

Correlates of Negative Attitudes towards Medication in People with Schizophrenia.

机构信息

Department of Social Psychiatry, National Institute of Mental Health, Klecany, Czech Republic.

Clinical Division of Social Psychiatry, University-Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.

出版信息

Psychiatr Q. 2019 Mar;90(1):159-169. doi: 10.1007/s11126-018-9618-z.

DOI:10.1007/s11126-018-9618-z
PMID:30478641
Abstract

Attitudes towards psychiatric medication are an important factor influencing the success of treatment. Mental health care in the region of Central and Eastern Europe remains biologically oriented, yet the attitudes of people with severe mental illnesses are largely unknown. In the present study, we aimed to analyze factors of attitudes toward psychopharmacological drugs among people with schizophrenia spectrum disorder who use community social services in the Czech Republic. Drug Attitude Inventory (DAI) was used as a primary research instrument and data were analyzed using a multivariable linear regression. The majority of respondents (78%) had positive attitudes towards psychopharmacological treatment. Additionally, attitudes towards psychopharmaceutic drugs did not differ with regard to sociodemographic characteristics except for family status. There was a significant negative correlation with the level of self-stigmatization and a significant positive correlation with the duration of treatment. Respondents who had repeated experiences with discontinuation of medication without a prior consultation with a psychiatrist had significantly worse attitudes towards medication than respondents without this experience. This study revealed evidence of a strong relationship between the attitudes toward medication and a history of discontinuation of taking medication and duration of treatment. Therefore, we suggest that interventions focused preventing the internalization of stigmatizing attitudes towards mental illness should be available to people with schizophrenia spectrum disorder, especially in the early stages of the illness - irrespective of the patient's age.

摘要

对精神科药物的态度是影响治疗成功的一个重要因素。中东欧地区的精神卫生保健仍然以生物学为导向,但严重精神疾病患者的态度在很大程度上是未知的。在本研究中,我们旨在分析在捷克共和国使用社区社会服务的精神分裂症谱系障碍患者对精神药理学药物的态度因素。药物态度量表(DAI)被用作主要研究工具,使用多变量线性回归分析数据。大多数受访者(78%)对精神药物治疗持积极态度。此外,除了家庭状况外,药物态度与社会人口学特征无关。自我污名化程度与治疗持续时间呈显著负相关,与治疗持续时间呈显著正相关。与没有事先与精神科医生协商就停药的经历相比,有重复停药经历的受访者对药物的态度明显较差。这项研究表明,药物态度与停药经历和治疗持续时间之间存在很强的关系。因此,我们建议,应该为精神分裂症谱系障碍患者提供干预措施,以防止对精神疾病的污名化态度内化,特别是在疾病的早期阶段 - 无论患者的年龄如何。

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The Effects of Group Psychoeducational Programme on Attitude toward Mental Illness in Families of Patients with Schizophrenia, 2014.团体心理教育项目对精神分裂症患者家庭中精神疾病态度的影响,2014年
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