Beutelmann Rainer, Laumen Geneviève, Tollin Daniel, Klump Georg M
Cluster of Excellence "Hearing4all," Animal Physiology and Behavior Group, Department of Neurosciences, School of Medicine and Health Sciences, Carl von Ossietzky University of Oldenburg, Oldenburg, Germany
Department of Physiology and Biophysics, School of Medicine, University of Colorado, Aurora, Colorado 80045
J Acoust Soc Am. 2015 Jan;137(1):EL71-7. doi: 10.1121/1.4903921.
Although auditory brainstem responses (ABRs), the sound-evoked brain activity in response to transient sounds, are routinely measured in humans and animals there are often differences in ABR waveform morphology across studies. One possible reason may be the method of stimulus calibration. To explore this hypothesis, click-evoked ABRs were measured from seven ears in four Mongolian gerbils (Meriones unguiculatus) using three common spectrum calibration strategies: Minimum phase filter, linear phase filter, and no filter. The results show significantly higher ABR amplitude and signal-to-noise ratio, and better waveform resolution with the minimum phase filtered click than with the other strategies.
尽管听觉脑干反应(ABRs),即对瞬态声音做出反应的声音诱发脑活动,在人类和动物中都有常规测量,但不同研究之间ABR波形形态往往存在差异。一个可能的原因可能是刺激校准方法。为了探究这一假设,使用三种常见的频谱校准策略:最小相位滤波器、线性相位滤波器和无滤波器,对四只蒙古沙鼠(长爪沙鼠)的七只耳朵进行了点击诱发ABR测量。结果表明,与其他策略相比,使用最小相位滤波点击时,ABR幅度和信噪比显著更高,波形分辨率更好。