Sagnier S, Poli M, Oysel-Mestre M, Corneloup O, Debruxelles S, Renou P, Rouanet F, Sibon I
Unité neuro-vasculaire, CHU de Bordeaux, place Amélie Raba-Léon, 33076 Bordeaux cedex, France; Unité neuro-vasculaire, pôle de neurosciences cliniques, hôpital Pellegrin, université Bordeaux Segalen, CHU de Bordeaux, place Amélie Raba-Léon, 33000 Bordeaux, France.
Unité neuro-vasculaire, CHU de Bordeaux, place Amélie Raba-Léon, 33076 Bordeaux cedex, France.
Rev Neurol (Paris). 2015 Feb;171(2):157-60. doi: 10.1016/j.neurol.2014.07.019. Epub 2015 Jan 21.
Caseous calcification of the mitral annulus (CCAM) is a rare complication of mitral annulus calcification (MAC). Whether CCAM should be considered as a cardiac source of stroke or a simple marker of atherosclerosis remains a matter of debate.
Herein, we report two patients with stroke and CCAM.
The first one was associated with extensive aortic arch atheroma, while CCAM was the only potential cause in the second case. Transthoracic echocardiography was normal in both cases and CCAM was diagnosed on transesophageal echocardiography.
These observations suggest that CCAM should be added to the list of minor cardioembolic sources of stroke but also requires a perfect control of vascular risk factors.
二尖瓣环干酪样钙化（CCAM）是二尖瓣环钙化（MAC）的一种罕见并发症。CCAM应被视为卒中的心脏来源还是单纯的动脉粥样硬化标志物仍存在争议。
在此，我们报告2例患有卒中和CCAM的患者。
第一例与广泛的主动脉弓动脉粥样硬化相关，而在第二例中CCAM是唯一的潜在病因。两例患者经胸超声心动图均正常，CCAM通过经食管超声心动图诊断。
这些观察结果表明，CCAM应被列入轻微心脏栓塞性卒中来源的清单中，但同时也需要对血管危险因素进行完善控制。
