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[Effects of non-lethal scalding on the density and affinity of beta adrenoreceptors in cardiac muscle in rats].

作者信息

Prostran M, Vujnov S, Savic J, Varagic V M, Lovric M, Bacic F

机构信息

Institut de Pharmacologie, Faculté de Médecine, Belgrade, Yougoslavie.

出版信息

C R Seances Soc Biol Fil. 1989;183(6):543-8.

PMID:2561963
Abstract

Our results indicate changes in both Bmax and KD of the beta-adrenergic receptors in the ventricular heart muscle of the rat, submitted to non-lethal scalding, even in the early posttraumatic period. The changes of heart, plasma and urine noradrenaline and adrenaline contents indicate significant increase in sympatho-adrenal activity after non-lethal scalding. The parallel changes of the beta-adrenergic receptor characteristics, which depend on the changes of catecholamines in the heart muscle and plasma only at certain time intervals after trauma, tend to preserve normal-control values.

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