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利用短期原代培养对肾近端小管电解质转运终末分化的研究。

Studies of terminal differentiation of electrolyte transport in the renal proximal tubule using short-term primary cultures.

作者信息

Larsson S H, Larsson L, Lechene C, Aperia A

机构信息

Department of Paediatrics, St. Göran's Children's Hospital, Stockholm, Sweden.

出版信息

Pediatr Nephrol. 1989 Jul;3(3):363-8. doi: 10.1007/BF00858547.

DOI:10.1007/BF00858547
PMID:2562016
Abstract

There are several lines of indirect evidence suggesting that the renal tubule cells have not yet reached terminal differentiation at birth. Methods used in cell biology can now be applied to study renal ontogeny. This review describes how primary cultures of proximal tubule cells from rats can be used to investigate developmental changes in Na permeability and Na-K-ATPase-mediated transport.

摘要

有几条间接证据表明，肾小管细胞在出生时尚未达到终末分化。细胞生物学中使用的方法现在可用于研究肾脏个体发育。这篇综述描述了如何利用大鼠近端小管细胞的原代培养来研究钠通透性和钠钾ATP酶介导转运的发育变化。

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Studies of terminal differentiation of electrolyte transport in the renal proximal tubule using short-term primary cultures.利用短期原代培养对肾近端小管电解质转运终末分化的研究。
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Role of protein kinase C in beta 2-adrenoceptor function in cultured rat proximal tubule epithelial cells.蛋白激酶C在培养的大鼠近端肾小管上皮细胞β2-肾上腺素能受体功能中的作用
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Studies on terminal differentiation of rat renal proximal tubular cells in culture: ouabain-sensitive K and Na transport.培养的大鼠肾近端小管细胞终末分化的研究：哇巴因敏感的钾和钠转运
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Beta 2-adrenergic function in cultured rat proximal tubule epithelial cells.培养的大鼠近端肾小管上皮细胞中的β2-肾上腺素能功能
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Short-term primary cultures in studies of post-natal maturation of the rat proximal tubule-proton and bicarbonate transport.
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本文引用的文献

1
Effect of normal development on compensatory renal growth.正常发育对肾代偿性生长的影响。
Kidney Int. 1980 Jul;18(1):29-35. doi: 10.1038/ki.1980.107.
2
Transport and metabolism of glucose by renal proximal tubular cells in primary culture.原代培养的肾近端小管细胞对葡萄糖的转运与代谢
Am J Physiol. 1984 Jun;246(6 Pt 2):F757-64. doi: 10.1152/ajprenal.1984.246.6.F757.
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Development of solute transport in rabbit proximal tubule. II. Morphologic segmentation.兔近端小管溶质转运的发育。II. 形态学分段
Am J Physiol. 1983 Sep;245(3):F391-407. doi: 10.1152/ajprenal.1983.245.3.F391.
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Na regulates growth of kidney epithelial cells induced by lowering extracellular K concentration.钠调节因降低细胞外钾浓度而诱导的肾上皮细胞生长。
Am J Physiol. 1984 Nov;247(5 Pt 1):C321-6. doi: 10.1152/ajpcell.1984.247.5.C321.
5
Development of solute transport in rabbit proximal tubule. III. Na-K-ATPase activity.兔近端小管溶质转运的发育。III. 钠钾ATP酶活性。
Am J Physiol. 1984 Jun;246(6 Pt 2):F845-52. doi: 10.1152/ajprenal.1984.246.6.F845.
6
Development of solute transport in rabbit proximal tubule. I. HCO-3 and glucose absorption.兔近端小管溶质转运的发育。I. HCO₃⁻和葡萄糖吸收。
Am J Physiol. 1983 Sep;245(3):F382-90. doi: 10.1152/ajprenal.1983.245.3.F382.
7
Characterization of primary rabbit kidney cultures that express proximal tubule functions in a hormonally defined medium.在激素限定培养基中表达近端小管功能的原代兔肾培养物的特性分析。
J Cell Biol. 1982 Oct;95(1):118-26. doi: 10.1083/jcb.95.1.118.
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Hormonal induction of Na-K-ATPase in developing proximal tubular cells.发育中的近端肾小管细胞中钠钾ATP酶的激素诱导作用。
Am J Physiol. 1981 Oct;241(4):F356-60. doi: 10.1152/ajprenal.1981.241.4.F356.
9
Growth of functional primary cultures of kidney epithelial cells in defined medium.在限定培养基中培养肾上皮细胞功能性原代培养物。
J Cell Physiol. 1980 Nov;105(2):369-78. doi: 10.1002/jcp.1041050220.
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Studies of renal cell function using cell culture techniques.
Am J Physiol. 1980 Jan;238(1):F1-9. doi: 10.1152/ajprenal.1980.238.1.F1.