O'Leary Thomas J, Morris Martyn G, Collett Johnny, Howells Ken
Department of Sport and Health Sciences, Oxford Brookes University, Gipsy Lane, Oxford, Oxon, OX3 0BP, United Kingdom.
Muscle Nerve. 2015 Oct;52(4):605-15. doi: 10.1002/mus.24584. Epub 2015 Aug 14.
Transcranial magnetic stimulation (TMS) is an important tool to examine neurological pathologies, movement disorders, and central nervous system responses to exercise, fatigue, and training. The reliability has not been examined in a functional locomotor knee extensor muscle.
Within- (n = 10) and between-day (n = 16) reliability of single and paired-paired pulse TMS was examined from the active vastus lateralis.
Motor evoked potential amplitude and cortical silent period duration showed good within- and between-day reliability (intraclass correlation coefficient [ICC] ≥ 0.82). Short- and long-interval intracortical inhibition (SICI and LICI, respectively) demonstrated good within-day reliability (ICC ≥ 0.84). SICI had moderate to good between-day reliability (ICC ≥ 0.67), but LICI was not repeatable (ICC = 0.47). Intracortical facilitation showed moderate to good within-day reliability (ICC ≥ 0.73) but poor to moderate reliability between days (ICC ≥ 0.51).
TMS can reliably assess cortical function in a knee extensor muscle. This may be useful to examine neurological disorders that affect locomotion.
经颅磁刺激（TMS）是检查神经病理学、运动障碍以及中枢神经系统对运动、疲劳和训练反应的重要工具。其在功能性运动膝关节伸肌中的可靠性尚未得到检验。
从活跃的股外侧肌检查单脉冲和双脉冲TMS的日内（n = 10）和日间（n = 16）可靠性。
运动诱发电位幅度和皮质静息期持续时间显示出良好的日内和日间可靠性（组内相关系数[ICC]≥0.82）。短间隔和长间隔皮质内抑制（分别为SICI和LICI）显示出良好的日内可靠性（ICC≥0.84）。SICI具有中度至良好的日间可靠性（ICC≥0.67），但LICI不可重复（ICC = 0.47）。皮质内易化显示出良好的日内可靠性（ICC≥0.73），但日间可靠性较差至中度（ICC≥0.51）。
TMS能够可靠地评估膝关节伸肌的皮质功能。这对于检查影响运动的神经疾病可能有用。
