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一名曾接受冠状动脉搭桥术的患者发生锁骨下动脉血栓形成,导致急性前壁心肌梗死并并发左臂缺血的治疗

Management of a subclavian artery thrombosis causing acute anterior wall infarction and concurrent left arm ischemia in a patient with prior coronary bypass.

作者信息

Akgüllü Çağdaş, Eryılmaz Ufuk, Zencir Cemil, Güngör Hasan

机构信息

Department of Cardiology, Adnan Menderes University Faculty of Medicine, Aydın, Turkey.

出版信息

Turk Kardiyol Dern Ars. 2014 Dec;42(8):751-5. doi: 10.5543/tkda.2014.80524.

DOI:10.5543/tkda.2014.80524
PMID:25620337
Abstract

We report a 57-year-old patient with acute anterior wall infarction with a history of a coronary baypass graft operation in 2007. He also had concurrent left arm cyanosis and severe pain. He had received diagnosis of pancreatic adenocarcinoma one month previously and had had his first chemotherapy in the previous week with gemcitabine and 5-fluorouracil. After the angiography, a giant thrombus was detected in the proximal left subclavian artery, deteriorating the flows of both left internal mammarian artery (LIMA) to left anterior descending (LAD) coronary artery graft, as well as the left brachial artery. The proximal subclavian artery was stented and good flow was achieved. Through the LIMA, the distal part of LAD, which was totally obstructed with probable distal thrombus embolization, was reached and a percutaneous balloon angioplasty performed. However, the no-reflow phenomenon was observed in distal LAD. A Fogarty traction of thrombus was performed successfully for the revascularization of the left arm. Approximately 30 minutes after the procedure, both angina and ST segment elevation in ECG were resolved under unfractioned heparin and nitroglycerin infusion. However, the patient died due to sepsis seven days after admission to hospital. In the literature, there are only a few previous reports on this rare clinical entity. The eitology, presentation, and the possible management strategies of this clinical entity is presented in this report.

摘要

我们报告一名57岁的患者,患有急性前壁心肌梗死,有2007年冠状动脉搭桥手术史。他同时伴有左臂发绀和剧痛。他在一个月前被诊断为胰腺腺癌,并于上周接受了第一次吉西他滨和5-氟尿嘧啶化疗。血管造影后,在左锁骨下动脉近端检测到一个巨大血栓,导致左乳内动脉(LIMA)至左前降支(LAD)冠状动脉搭桥以及左肱动脉的血流均恶化。对锁骨下动脉近端进行了支架置入,血流恢复良好。通过LIMA到达了完全阻塞且可能存在远端血栓栓塞的LAD远端部分,并进行了经皮球囊血管成形术。然而,在LAD远端观察到了无复流现象。成功地进行了血栓的Fogarty牵引以实现左臂血管重建。术后约30分钟,在输注普通肝素和硝酸甘油的情况下,心绞痛和心电图ST段抬高均得到缓解。然而,患者在入院七天后因败血症死亡。在文献中,关于这种罕见临床实体的先前报道很少。本报告介绍了该临床实体的病因、表现及可能的治疗策略。

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Management of a subclavian artery thrombosis causing acute anterior wall infarction and concurrent left arm ischemia in a patient with prior coronary bypass.一名曾接受冠状动脉搭桥术的患者发生锁骨下动脉血栓形成,导致急性前壁心肌梗死并并发左臂缺血的治疗
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