Muheremu Aikeremujiang, Niu Xiaohui
Department of Orthopedic Oncology Surgery, Beijing JiShui Tan Hospital, Beijing 100035, P.R. China.
Oncol Lett. 2015 Feb;9(2):522-526. doi: 10.3892/ol.2014.2728. Epub 2014 Nov 21.
The aim of the present study was to investigate positron emission tomography (PET)/computed tomography (CT) and its applications for the diagnosis and treatment of bone tumors. The advantages and disadvantages of PET/CT were also evaluated and compared with other imaging methods and the prospects of PET/CT were discussed. The PubMed, Medline, Elsevier, Wanfang and China International Knowledge Infrastructure databases were searched for studies published between 1995 and 2013, using the terms 'PET/CT', 'positron emission tomography', 'bone tumor', 'osteosarcoma', 'giant cell bone tumor' and 'Ewing sarcoma'. All the relevant information was extracted and analyzed. A total of 73 studies were selected for the final analysis. The extracted information indicated that at present, PET/CT is the imaging method that exhibits the highest sensitivity, specificity and accuracy. Although difficulties and problems remain to be solved, PET/CT is a promising non-invasive method for the diagnostic evaluation of and clinical guidance for bone tumors.
本研究的目的是探讨正电子发射断层扫描(PET)/计算机断层扫描(CT)及其在骨肿瘤诊断和治疗中的应用。同时评估了PET/CT的优缺点,并与其他成像方法进行比较,还讨论了PET/CT的前景。通过检索PubMed、Medline、Elsevier、万方和中国知网数据库,查找1995年至2013年间发表的使用“PET/CT”“正电子发射断层扫描”“骨肿瘤”“骨肉瘤”“骨巨细胞瘤”和“尤因肉瘤”等关键词的研究。提取并分析所有相关信息。最终选取73项研究进行分析。提取的信息表明,目前PET/CT是灵敏度、特异性和准确性最高的成像方法。尽管仍有困难和问题有待解决,但PET/CT是一种用于骨肿瘤诊断评估和临床指导的有前景的非侵入性方法。