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未来种植位点开发中的水压式上颌窦提升技术:人体活检的临床及组织形态计量学分析

Hydraulic sinus lift technique in future site development: clinical and histomorphometric analysis of human biopsies.

作者信息

Andreasi Bassi Mirko, Lopez Michele Antonio, Confalone Luca, Carinci Francesco

机构信息

*Private Practitioner, Rome, Italy. †Private Practitioner, Rome, Italy. ‡Private Practitioner, Rome, Italy. §Professor and Director, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.

出版信息

Implant Dent. 2015 Feb;24(1):117-24. doi: 10.1097/ID.0000000000000200.

Abstract

PURPOSE

The fluid-dynamic technique is characterized by the hydraulic detachment of the mucosa and simultaneous filling of the sub-Schneiderian space, with a graft material of paste-like consistency.

MATERIALS AND METHODS

Authors performed 13 future site developments, on as many patients (4 men; 9 women; age 49.46 ± 12.44 years), using a nanocrystalline hydroxyapatite dispersed in an aqueous matrix as graft material. In the second stage, performed at 5.96 ± 1.72 months, 13 implants were placed after harvesting bone biopsies from the regenerated sites. The above samples were subjected to histological and histomorphometric analysis. The histomorphometric results were then compared with the bone density, measured in Hounsfield units.

RESULTS

The average percentage of vital bone was of 29.08% ± 14.7%, whereas the bone marrow and graft material were 59.75% ± 11.19% and 11.16% ± 10.88%, respectively. The percentage of vital bone has a significant correlation with the bone density of the recipient site (P = 0.003117). In contrast, the bone marrow (P = 0.08692) and the graft (P = 0.0799) do not show a significant correlation with this parameter.

CONCLUSIONS

The results suggest the validity of the method in the regeneration of bone volume in the subantral region.

摘要

目的

流体动力学技术的特点是黏膜水分离,同时用膏状稠度的移植材料填充施耐德氏下间隙。

材料与方法

作者对13例患者(4名男性;9名女性;年龄49.46±12.44岁)进行了13次未来位点开发,使用分散在水性基质中的纳米晶羟基磷灰石作为移植材料。在第二阶段,于5.96±1.72个月时进行,从再生位点采集骨活检后植入13枚种植体。对上述样本进行组织学和组织形态计量学分析。然后将组织形态计量学结果与以亨氏单位测量的骨密度进行比较。

结果

活骨的平均百分比为29.08%±14.7%,而骨髓和移植材料分别为59.75%±11.19%和11.16%±10.88%。活骨百分比与受体位点的骨密度有显著相关性(P = 0.003117)。相比之下,骨髓(P = 0.08692)和移植材料(P = 0.0799)与该参数无显著相关性。

结论

结果表明该方法在窦下区域骨量再生中的有效性。

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