Campobasso O, Andrion A, Mancuso M, De Simone M, Ribotta M
Servizio di Anatomia Patologica, Ospedale Maria Vittoria, Torino.
Ann Osp Maria Vittoria Torino. 1989;31:9-24.
The prognostic significance of age, sex, location of the tumor in the various lobes, size, histological type, node metastases, local extent and stage has been studied in a series of 742 surgically resected lung carcinomas. The histological type was a very important prognostic factor: the highest survival was observed in epidermoid carcinomas, followed by adenocarcinomas, anaplastic large cell carcinomas, and anaplastic small cell carcinomas. The stage, as well, except for the adenocarcinoma, bore heavily on the prognosis; however, in small stage I tumours, the postoperative survival was independent from the histological type. The presence of lymph node metastases resulted in an extremely poor survival, except for the epidermoid carcinoma. The size of the tumours, excluding adenocarcinomas, was an important prognostic factor provided lymph node metastases were absent. No significant differences in survival according to the location in different lobes could be ascertained.
在一组742例接受手术切除的肺癌病例中,研究了年龄、性别、肿瘤在各肺叶的位置、大小、组织学类型、淋巴结转移情况、局部侵犯范围和分期的预后意义。组织学类型是一个非常重要的预后因素:在表皮样癌中观察到最高的生存率,其次是腺癌、间变性大细胞癌和间变性小细胞癌。除腺癌外,分期对预后也有很大影响;然而,在小的I期肿瘤中,术后生存率与组织学类型无关。除表皮样癌外,淋巴结转移的存在导致生存率极低。除腺癌外,如果没有淋巴结转移,肿瘤大小是一个重要的预后因素。根据肿瘤在不同肺叶的位置,未发现生存率有显著差异。