Imai Hisao, Kiyohara Yoshio, Yoshikawa Shusuke, Kusutani Nao, Ono Akira, Taira Tetsuhiko, Kenmotsu Hirotsugu, Harada Hideyuki, Naito Tateaki, Murakami Haruyasu, Sano Takehisa, Fuji Hiroshi, Endo Masahiro, Nakajima Takashi, Takahashi Toshiaki
Division of Thoracic Oncology, Shizuoka Cancer Center, Suntou-gun, Shizuoka 411-8777, Japan.
Division of Dermatology, Shizuoka Cancer Center, Suntou-gun, Shizuoka 411-8777, Japan.
Oncol Lett. 2015 Feb;9(2):657-660. doi: 10.3892/ol.2014.2782. Epub 2014 Dec 9.
Primary cancer of the trachea is rare and accounts for only 0.1-0.4% of all newly diagnosed respiratory tract cancers, worldwide. In the present study, a case of primary tracheal malignant melanoma, a particularly rare type of cancer, is reported. A 68-year-old male presented with a cough and bloody sputum. A chest computed tomography scan revealed a 25×20×15-mm tracheal tumor, located immediately above the carina, which reduced the cross-sectional area of the trachea by ~90%. Histopathological analysis of biopsy specimens determined a diagnosis of malignant melanoma. The patient was treated with argon plasma coagulation and chemoradiotherapy, which restored airway patency, however, metastasis was detected in the lungs. The patient refused further treatment and received palliative care. Subsequently, the patient succumbed to the disease within four months. Thus, although primary malignant melanoma of the trachea is extremeley rare, the possibility should be considered during diagnosis.
气管原发性癌很罕见，在全球范围内仅占所有新诊断呼吸道癌症的0.1 - 0.4%。在本研究中，报告了一例原发性气管恶性黑色素瘤，这是一种极其罕见的癌症类型。一名68岁男性出现咳嗽和咯血症状。胸部计算机断层扫描显示，在气管隆突上方有一个25×20×15毫米的气管肿瘤，使气管横截面积减少了约90%。活检标本的组织病理学分析确诊为恶性黑色素瘤。该患者接受了氩等离子体凝固和放化疗，气道得以恢复通畅，但肺部检测到转移。患者拒绝进一步治疗并接受了姑息治疗。随后，患者在四个月内死于该疾病。因此，尽管气管原发性恶性黑色素瘤极其罕见，但在诊断时应考虑到这种可能性。
