Cheng Bo, Cai Qiliang, Wu Yudong, Zhao Yan, Guo Qi, Li Gang, Zhang Xuening, Zhang Aimin, Niu Yuanjie
Department of Urology, Shengli Oil Field Central Hospital, Dongying, Shandong 257034, P.R. China.
Department of Urology, The Second Hospital of Tianjin Medical University, Tianjin Institute of Urology, Tianjin 300211, P.R. China.
Oncol Lett. 2015 Feb;9(2):829-832. doi: 10.3892/ol.2014.2729. Epub 2014 Nov 24.
The aim of the present study was to investigate the clinical characteristics and management of primary renal sinus tumors. We retrospectively analyzed three cases of primary renal sinus tumors. The first patient was a 33-year-old man who presented with right flank pain for 6 months. Based on the imaging results, the patient was diagnosed with renal sinus tumor. The second case was a 34-year-old woman who presented with sudden lumbago in the right flank for 3 days. The imaging results confirmed the diagnosis of right renal angiomyolipoma. The third case was a 55-year-old woman with flank pain, which had persisted for 1 year. The imaging tests revealed lipoma of the left renal sinus. All three cases underwent surgical procedures. The first case was diagnosed with benign angioleiomyoma following pathological analysis. During surgery, the tumor was ablated and the kidney was spared. The second case was scheduled for tumor enucleating, but a nephrectomy was performed due to serious hemorrhaging and a damaged renal pelvis. Pathological analysis identified angiomyolipoma. The third case was scheduled for lipoma enucleating; however, nephrectomy was performed as the tumor encapsulated the renal vascular pedicle. Pathological analysis revealed lipoma. In the three cases, no relapse over 3 years, 10 months and 4 years of follow-up, respectively, was observed. In addition, this review examined previous literature and concluded that the occurrence of tumors in the renal sinus is rare and the majority of such tumors are benign. Furthermore, cases are easily misdiagnosed as renal pelvic tumors. Computed tomography, magnetic resonance imaging and intravenous urography are the best imaging examination methods for differential diagnosis. In conclusion, surgery is the usual approach for the treatment of renal sinus tumors and radical nephrectomy should be performed for malignant tumors.
本研究的目的是探讨原发性肾窦肿瘤的临床特征及治疗方法。我们回顾性分析了3例原发性肾窦肿瘤病例。第一例患者为33岁男性,右侧腰痛6个月。根据影像学结果,该患者被诊断为肾窦肿瘤。第二例是一名34岁女性,右侧腰部突然疼痛3天。影像学结果确诊为右肾血管平滑肌脂肪瘤。第三例是一名55岁女性,腰痛持续1年。影像学检查显示左肾窦脂肪瘤。所有3例患者均接受了手术治疗。第一例经病理分析诊断为良性血管平滑肌瘤。手术中,肿瘤被切除,肾脏得以保留。第二例计划行肿瘤剜除术,但因严重出血和肾盂损伤而进行了肾切除术。病理分析确诊为血管平滑肌脂肪瘤。第三例计划行脂肪瘤剜除术;然而,由于肿瘤包裹了肾血管蒂,故进行了肾切除术。病理分析显示为脂肪瘤。在这3例患者中,分别随访3年、10个月和4年,均未观察到复发。此外,本综述查阅了既往文献并得出结论,肾窦肿瘤的发生较为罕见,且大多数此类肿瘤为良性。此外,病例容易被误诊为肾盂肿瘤。计算机断层扫描、磁共振成像和静脉肾盂造影是鉴别诊断的最佳影像学检查方法。总之,手术是治疗肾窦肿瘤的常用方法,对于恶性肿瘤应行根治性肾切除术。