Lin Zhimin, Chng Jack Kian, Chong Tze Tec, Soo Khee Chee
Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Department of Vascular Surgery, Singapore General Hospital, Singapore.
Int J Surg Case Rep. 2014;5(8):444-7. doi: 10.1016/j.ijscr.2014.05.001. Epub 2014 May 22.
Renal squamous cell carcinoma (RSCC) is a rare tumor that is usually diagnosed late as a locally advanced malignancy with adjacent structure involvement. Radical surgical resection with negative margins is the mainstay of treatment, as it is correlated with improved survival, while other modalities of treatment have been shown to have limited efficacy.
We report a case of a 56 year old gentleman with right RSCC with tumor encasing the inferior vena cava (IVC), treated successfully with surgical resection.
The surgical management of vascular involvement of similar tumors has not been discussed in-depth in the literature. Surgical resection of the IVC without reconstruction can be done successfully in the circumstance of good collateral circulation; otherwise IVC resection with reconstruction will be necessary.
Radical resection with clear margins of RSCC tumors with vascular involvement is feasible in selected circumstances.
肾鳞状细胞癌(RSCC)是一种罕见肿瘤,通常在诊断时已发展为局部晚期恶性肿瘤并累及相邻结构,确诊较晚。切缘阴性的根治性手术切除是主要治疗方法,因为这与生存率提高相关,而其他治疗方式疗效有限。
我们报告一例56岁男性右肾鳞状细胞癌患者,肿瘤包绕下腔静脉(IVC),经手术切除成功治疗。
文献中尚未深入讨论类似肿瘤血管受累的手术处理。在侧支循环良好的情况下,可不进行重建直接成功切除下腔静脉;否则,则需要进行下腔静脉切除并重建。
在特定情况下,对伴有血管受累的肾鳞状细胞癌肿瘤进行切缘清晰的根治性切除是可行的。