Yashiro Masakazu, Matsuoka Tasuku
Masakazu Yashiro, Tasuku Matsuoka, Department of Surgical Oncology, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan.
World J Gastrointest Surg. 2015 Jan 27;7(1):1-9. doi: 10.4240/wjgs.v7.i1.1.
The sentinel node (SN) technique has been established for the treatment of some types of solid cancers to avoid unnecessary lymphadenectomy. If node disease were diagnosed before surgery, minimal surgery with omission of lymph node dissection would be an option for patients with early gastric cancer. Although SN biopsy has been well ascertained in the treatment of breast cancer and melanoma, SN navigation surgery (SNNS) in gastric cancer has not been yet universal due to the complicated lymphatic flow from the stomach. Satisfactory establishment of SNNS will result in the possible indication of minimally invasive surgery of gastric cancer. However, the results reported in the literature on SN biopsy in gastric cancer are widely divergent and many issues are still to be resolved, such as the collection method of SN, detection of micrometastasis in SN, and clinical benefit. The difference in the procedural technique and learning phase of surgeons is also varied the accuracy of SN mapping. In this review, we outline the current status of application for SNNS in gastric cancer.
前哨淋巴结（SN）技术已被确立用于某些类型实体癌的治疗，以避免不必要的淋巴结清扫术。如果在手术前诊断出淋巴结疾病，对于早期胃癌患者，省略淋巴结清扫的微创手术将是一种选择。尽管SN活检在乳腺癌和黑色素瘤的治疗中已得到充分证实，但由于胃的淋巴引流复杂，胃癌的SN导航手术（SNNS）尚未普及。SNNS的满意确立将使胃癌微创手术成为可能。然而，文献报道的胃癌SN活检结果差异很大，许多问题仍有待解决，如SN的采集方法、SN中微转移的检测以及临床获益。外科医生手术技术和学习阶段的差异也会影响SN定位的准确性。在本综述中，我们概述了SNNS在胃癌中的应用现状。
