Chen Cheng, Tsow Francis, Xian Xiaojun, Forzani Erica, Tao Nongjian, Tsui Raymond
Biodesign Institute, Arizona State University, Tempe, AZ, 85287-5801, USA.
Methods Mol Biol. 2015;1256:201-11. doi: 10.1007/978-1-4939-2172-0_14.
A portable chemical sensing system that integrates sample preconcentration, separation and detection as well as wireless communication functionalities into a compact, wearable format can provide continuous and real-time monitoring of volatile organic compounds in the environment. The sensing modality relies on tuning forks coated with molecularly imprinted polymers that, in conjunction with sample preconcentration, offer selective detection down to parts-per-billion levels. The use of capillary columns allows individual components of complex mixtures to be detected at these highly sensitive levels even in the presence of interferents. The wireless capability facilitates the utilization of a paired smartphone as the user interface as well as a vehicle for additional processing and storage of the measured data. This integrated approach offers a cost-effective and reliable platform for personal exposure assessment.
一种便携式化学传感系统，将样品预浓缩、分离与检测以及无线通信功能集成到紧凑的可穿戴形式中，能够对环境中的挥发性有机化合物进行连续实时监测。该传感方式依赖于涂有分子印迹聚合物的音叉，结合样品预浓缩，可实现低至十亿分之一水平的选择性检测。即使存在干扰物，使用毛细管柱也能在这些高灵敏度水平下检测复杂混合物的各个成分。无线功能便于将配对的智能手机用作用户界面以及用于对测量数据进行额外处理和存储的载体。这种集成方法为个人暴露评估提供了一个经济高效且可靠的平台。
