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可穿戴环境监测器,量化个人环境中挥发性有机化合物暴露情况。

Wearable Environmental Monitor To Quantify Personal Ambient Volatile Organic Compound Exposures.

机构信息

Mechanical and Aerospace Engineering , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.

Department of Internal Medicine , University of California, Davis , 4150 V Street, Suite 3400, Sacramento , California 95817 , United States.

出版信息

ACS Sens. 2019 May 24;4(5):1358-1364. doi: 10.1021/acssensors.9b00304. Epub 2019 May 10.

Abstract

Air pollution can cause acute and chronic health problems. It has many components, and one component of interest is volatile organic compounds (VOCs). While the outdoor environment may have regulations regarding exposure limits, the indoor environment is often unregulated and VOCs often appear in greater concentrations in the indoor environment. Therefore, it is equally critical to monitor both the indoor and outdoor environments for ambient chemical levels that an individual person is exposed to. While a number of different chemical detectors exist, most lack the ability to provide portable monitoring. We have developed a portable and wearable sampler that collects environmental VOCs in a person's immediate "exposure envelope" onto custom micro-preconcentrator chips for later benchtop analysis. The system also records ambient temperature and humidity and the GPS location during sampling, and the chip cartridges can be used in sequence over time to complete a profile of individual chemical exposure over the course of hours/days/weeks/months. The system can be programmed to accumulate sample for various times with varying periodicity. We first tested our sampler in the laboratory by completing calibration curves and testing saturation times for various common chemicals. The sampler was also tested in the field by collecting both indoor and outdoor personal exposure samples. Additionally under IRB approval, a teenaged volunteer wore the sampler for 5 days during which it sampled periodically throughout a 12 h period each day and the volunteer replaced the micro-preconcentrator chip each day.

摘要

空气污染会导致急性和慢性健康问题。它有许多成分,其中一个感兴趣的成分是挥发性有机化合物(VOCs)。虽然室外环境可能有关于暴露限制的规定,但室内环境通常不受监管,VOCs 往往在室内环境中出现更高的浓度。因此,监测室内和室外环境中个人暴露的环境化学水平同样至关重要。虽然存在许多不同的化学探测器,但大多数都缺乏提供便携式监测的能力。我们开发了一种便携式和可穿戴的采样器,可以将人的直接“暴露包络”中的环境 VOCs 收集到定制的微预浓缩器芯片上,以便以后进行台式分析。该系统还记录采样期间的环境温度和湿度以及 GPS 位置,并且随着时间的推移,芯片盒可以依次使用,以完成数小时/数天/数周/数月内个人化学暴露的情况。该系统可以编程以不同的时间间隔和周期性来累积样品。我们首先在实验室中通过完成各种常见化学物质的校准曲线和测试饱和时间来测试我们的采样器。采样器还在现场进行了测试,采集了室内和室外个人暴露样本。此外,在 IRB 批准下,一名青少年志愿者佩戴采样器 5 天,每天在 12 小时期间定期采样,志愿者每天更换微预浓缩器芯片。

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