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[黑色素瘤腋窝淋巴结清扫术后腋窝网状综合征:5例]

[Axillary web syndrome following axillary lymph node dissection for melanoma: 5 cases].

作者信息

Bourguignon D, Aktouf G, Coquerel D, Auquit-Auckbur I

机构信息

Service de chirurgie plastique reconstructrice et esthétique, CHU Charles-Nicolle, 1, rue de Germont, 76031 Rouen cedex, France.

Service de chirurgie plastique reconstructrice et esthétique, CHU Charles-Nicolle, 1, rue de Germont, 76031 Rouen cedex, France.

出版信息

Ann Dermatol Venereol. 2015 Feb;142(2):94-8. doi: 10.1016/j.annder.2014.11.019. Epub 2015 Jan 24.

DOI:10.1016/j.annder.2014.11.019
PMID:25626622
Abstract

BACKGROUND

Axillary web syndrome is a rare disease similar to Mondor's disease and is usually seen after axillary surgery. Herein, we describe five new cases, all of which occurred in a setting of melanoma.

PATIENTS AND METHODS

Five patients presented axillary web syndrome following sentinel node surgery, adenectomy or axillary curettage in a setting of melanoma. Therapy involving analgesics and physiotherapy to snap the cord-like structure helped accelerate resolution.

DISCUSSION

Some debate continues to surround the physiopathology of axillary web syndrome in the literature, particularly regarding its relationship with Mondor's disease, which is considered to result from superficial venous thrombosis. The lymphatic and myofascial explanation for the syndrome appears to us to be more coherent and justifies the non-aggressive therapeutic approach we adopt for our patients, who receive assurances about the benign nature of their condition and the absence of sequelae.

CONCLUSION

Axillary surgery in patients presenting melanoma appears to be a risk factor for axillary web syndrome. No relationship has as yet been demonstrated between this syndrome and the presence of axillary metastases.

摘要

背景

腋窝网状综合征是一种类似于蒙多氏病的罕见疾病,通常在腋窝手术后出现。在此,我们描述了五例新病例,所有病例均发生在黑色素瘤患者中。

患者与方法

五例患者在黑色素瘤背景下,于前哨淋巴结手术、腺切除术或腋窝刮除术后出现腋窝网状综合征。采用镇痛药和物理疗法以松解条索状结构的治疗方法有助于加速症状缓解。

讨论

关于腋窝网状综合征的病理生理学,文献中仍存在一些争议,特别是其与蒙多氏病的关系,后者被认为是由浅静脉血栓形成所致。在我们看来,该综合征的淋巴和肌筋膜学解释更为合理,这也证明了我们对患者采取的非积极治疗方法的合理性,我们向患者保证其病情的良性性质以及不会留下后遗症。

结论

黑色素瘤患者的腋窝手术似乎是腋窝网状综合征的一个危险因素。目前尚未证实该综合征与腋窝转移灶的存在之间存在关联。

相似文献

1
[Axillary web syndrome following axillary lymph node dissection for melanoma: 5 cases].[黑色素瘤腋窝淋巴结清扫术后腋窝网状综合征:5例]
Ann Dermatol Venereol. 2015 Feb;142(2):94-8. doi: 10.1016/j.annder.2014.11.019. Epub 2015 Jan 24.
2
[Axillary web syndrome--a variant of Mondor's disease, following excision of an accessory breast].[腋网综合征——副乳切除术后蒙多氏病的一种变体]
Harefuah. 2011 Dec;150(12):893-4, 937, 936.
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Lymph node dissection in patients with malignant melanoma is associated with high risk of morbidity.恶性黑色素瘤患者进行淋巴结清扫术会带来较高的发病风险。
Dan Med J. 2012 Jun;59(6):A4441.
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Morbidity and recurrence after completion lymph node dissection following sentinel lymph node biopsy in cutaneous malignant melanoma.皮肤恶性黑色素瘤前哨淋巴结活检后完成淋巴结清扫的发病率和复发情况。
Ann Surg. 2008 Apr;247(4):687-93. doi: 10.1097/SLA.0b013e318161312a.
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Combined ipsilateral neck and axillary lymphadenectomy for metastatic skin cancers: a case series and surgical tips.同侧颈部和腋窝淋巴结切除术治疗转移性皮肤癌:病例系列和手术技巧。
J Plast Reconstr Aesthet Surg. 2013 Aug;66(8):1082-7. doi: 10.1016/j.bjps.2013.04.044. Epub 2013 May 7.
6
Axillary web syndrome or cording, a variant of mondor disease, following axillary surgery.腋窝网状综合征或索状带,是蒙多氏病的一种变体,发生于腋窝手术后。
Arch Dermatol. 2009 Oct;145(10):1199-200. doi: 10.1001/archdermatol.2009.239.
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Mondor's disease after bilateral axillary node biopsy.双侧腋窝淋巴结活检后发生蒙多氏病。
Arch Gynecol Obstet. 2006 Mar;273(6):374-7. doi: 10.1007/s00404-005-0038-6. Epub 2005 Dec 23.
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Complete lymph node dissection for regional nodal metastasis.行区域淋巴结转移的彻底淋巴结清扫术。
Clin Plast Surg. 2010 Jan;37(1):113-25. doi: 10.1016/j.cps.2009.07.002.
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Chylorrhea after axillary lymph node dissection.腋窝淋巴结清扫术后乳糜漏
Eur J Surg Oncol. 2007 Oct;33(8):1042-3. doi: 10.1016/j.ejso.2007.04.019. Epub 2007 Jun 22.
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Altered drainage patterns in patients with melanoma and previous axillary dissection.黑色素瘤和既往腋窝清扫术患者引流模式的改变。
J Dermatol. 2013 Jul;40(7):564-6. doi: 10.1111/1346-8138.12143. Epub 2013 Apr 17.