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视盘黑色素细胞瘤的自体荧光与光谱域光学相干断层扫描

Autofluorescence and spectral-domain optical coherence tomography of optic disk melanocytoma.

作者信息

Guerra Ricardo Luz Leitão, Marback Eduardo Ferrari, Silva Igor Sandes Pessoa da, Maia Junior Otacílio de Oliveira, Marback Roberto Lorens

机构信息

Clínica de Olhos Leitão Guerra, Salvador, BA, Brazil.

Department of Ophthalmology, Universidade Federal da Bahia, Salvador, BA, Brazil.

出版信息

Arq Bras Oftalmol. 2014 Nov-Dec;77(6):400-2. doi: 10.5935/0004-2749.20140100.

DOI:10.5935/0004-2749.20140100
PMID:25627191
Abstract

The authors report fundus autofluorescence (FAF) and spectral-domain optical coherence tomography (OCT) findings of two consecutive patients who presented with optic disk melanocytoma (ODM). A retrospective study was performed by reviewing medical records and ophthalmic imaging examinations. Optical coherence tomography findings were sloped and brightly reflective anterior tumor surface, adjacent retinal desorganization and abrupt posterior optical shadowing. Vitreous seeds were found in one patient. Fundus autofluorescence revealed outstanding hypoautofluorescence at the tumor area and isoautofluorescence at the remaining retina. Optical coherence tomography findings of the reported cases are consistent with those reported in the reviewed literature. Fundus autofluorescence has been used in the assessment of choroidal melanocytic tumors, but not yet in melanocytomas. We assume that this is the first report of these findings and believe that when its pattern has become clearly defined, fundus autofluorescence will be a useful tool to avoid misdiagnosis in suspicious cases and for follow-up.

摘要

作者报告了两名连续出现视盘黑素细胞瘤(ODM)患者的眼底自发荧光(FAF)和光谱域光学相干断层扫描(OCT)结果。通过回顾病历和眼科成像检查进行了一项回顾性研究。光学相干断层扫描结果显示肿瘤前表面倾斜且反射明亮,相邻视网膜结构紊乱以及后部突然出现光学阴影。在一名患者中发现了玻璃体种子。眼底自发荧光显示肿瘤区域有明显的低自发荧光,其余视网膜为等自发荧光。报告病例的光学相干断层扫描结果与文献报道一致。眼底自发荧光已用于脉络膜黑素细胞肿瘤的评估,但尚未用于黑素细胞瘤。我们认为这是这些发现的首次报告,并相信当其模式明确后,眼底自发荧光将成为避免可疑病例误诊和进行随访的有用工具。

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引用本文的文献

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Ocular circulation change in optic disc melanocytoma - a case report and a review of the literature.视盘黑色素细胞瘤的眼循环变化——一例报告及文献复习。
BMC Ophthalmol. 2023 Jan 23;23(1):33. doi: 10.1186/s12886-023-02785-9.
2
Optic disc melanocytoma: a case report.视盘黑素细胞瘤:病例报告。
Rom J Ophthalmol. 2021 Jan-Mar;65(1):89-92. doi: 10.22336/rjo.2021.18.
3
Clinical and Spectral-Domain Optical Coherence Tomography Appearance of Optic Disc Melanocytoma: A New Classification and Differentiation from Pigmented Choroidal Lesions.
视盘黑色素细胞瘤的临床及频域光学相干断层扫描表现:一种新的分类及与色素性脉络膜病变的鉴别
Ocul Oncol Pathol. 2017 Jul;3(2):142-148. doi: 10.1159/000453110. Epub 2016 Dec 14.
4
Infrared autofluorescence, short-wave autofluorescence and spectral-domain optical coherence tomography of optic disk melanocytomas.视盘黑色素细胞瘤的红外自发荧光、短波自发荧光及谱域光学相干断层扫描
Int J Ophthalmol. 2016 May 18;9(5):713-6. doi: 10.18240/ijo.2016.05.13. eCollection 2016.