Marques Wanessa Vieira, Cruz Vitor Alves, Rego Jozelia, da Silva Nilzio Antonio
Faculdade de Medicina, Universidade Federal de Goiás, Goiânia, GO, Brasil.
Serviço de Reumatologia, Hospital das Clínicas, Faculdade de Medicina, Universidade Federal de Goiás, Goiânia, GO, Brasil.
Rev Bras Reumatol. 2014 Sep-Oct;54(5):404-8. doi: 10.1016/j.rbr.2014.03.019. Epub 2014 Jul 6.
Identify fall prevalence in the last 12 months among patients with rheumatoid arthritis (RA) and verify the influence of disease activity and physical function in the risk of falls.
43 patients with RA participated in this study. The following parameters were evaluated: clinical aspects; fall occurrence in the last 12 months; ESR (mm/h); pain on a visual analogue scale (VAS) ranging from 0 to 10cm; disease activity, measured by the Disease Activity Score 28/ESR (DAS-28/ESR); physical function, assessed by the Health Assessment Questionnaire (HAQ); and risk of falling, assessed by two tests, the 5-time sit down-to-stand up test (SST5) and the timed get up and go test (TUG).
The fall prevalence in the last 12 months was 30.2% (13/43). The HAQ total score was the independent risk factor that had significant influence on SST5 performance, and the other variables did not succeeded to explain the SST5 variability. HAQ explained 42.9% of SST5 variability (P<0.001, adjusted R(2)=0.429). HAQ total score and ESR had a significant influence on TUG score performance. Together, these two variables explained 68.8% of the total variation in TUG score (adjusted R(2)=0.688).
Patients with RA have high fall prevalence and the functional disability represents the main factor related to falls risk.
确定类风湿关节炎（RA）患者在过去12个月中的跌倒发生率，并验证疾病活动度和身体功能对跌倒风险的影响。
43例RA患者参与了本研究。评估了以下参数：临床情况；过去12个月内的跌倒发生情况；血沉（mm/h）；视觉模拟量表（VAS，范围为0至10cm）上的疼痛程度；通过疾病活动评分28/血沉（DAS-28/ESR）测量的疾病活动度；通过健康评估问卷（HAQ）评估的身体功能；以及通过两项测试评估的跌倒风险，即5次坐立试验（SST5）和计时起立行走试验（TUG）。
过去12个月的跌倒发生率为30.2%（13/43）。HAQ总分是对SST5表现有显著影响的独立危险因素，其他变量未能解释SST5的变异性。HAQ解释了SST5变异性的42.9%（P<0.001，调整后R²=0.429）。HAQ总分和血沉对TUG评分表现有显著影响。这两个变量共同解释了TUG评分总变异的68.8%（调整后R²=0.688） 。
RA患者跌倒发生率较高，功能残疾是与跌倒风险相关的主要因素。
