Feisther Vódice Amoroz, Ulson de Souza Antônio Augusto, Trigueros Daniela Estelita Goes, de Mello Josiane Maria Muneronde, de Oliveira Déborade, Guelli Ulson de Souza Selene M A
Departamento de Engenharia Química, Laboratório de Transferência de Massa, Universidade Federal de Santa Catarina, PO Box 476, CEP 88, 040-900, Florianópolis, SC, Brazil.
Bioprocess Biosyst Eng. 2015 Jul;38(7):1233-41. doi: 10.1007/s00449-015-1364-0. Epub 2015 Jan 28.
The biodegradation kinetics of BTX compounds (benzene, toluene, and xylene) individually and as mixtures was studied using models with different levels of sophistication. To compare the performance of the unstructured models applied in this work we used experimental data obtained here and some results published in the literature. The system description was based on the material balances of key components for batch operations, where the Monod and Andrews models were applied to predict the biodegradation of individual substrates. To simulate the biodegradation kinetics of substrate mixtures, models of substrate inhibition were applied along with the Sum Kinetics with Interaction Parameters (SKIP) models, where for two-component association toluene-xylene SKIP model presented better performance and for tri-component association benzene-toluene-xylene, the uncompetitive inhibition model was better. The kinetic parameters were estimated via a global search method known as Particle Swarm Optimization (PSO). The main result of this study is that the sophisticated biodegradation kinetics of BTX mixtures can be successfully described by applying the SKIP model, with the main advantage being the consideration of the substrate interactions.
利用不同复杂程度的模型研究了苯系物（苯、甲苯和二甲苯）单独及混合时的生物降解动力学。为比较本研究中应用的非结构化模型的性能，我们使用了此处获得的实验数据以及文献中发表的一些结果。系统描述基于间歇操作关键组分的物料平衡，其中应用莫诺德模型和安德鲁斯模型预测单个底物的生物降解。为模拟底物混合物的生物降解动力学，应用了底物抑制模型以及带相互作用参数的总动力学（SKIP）模型，其中对于甲苯 - 二甲苯二元组合，SKIP模型表现更佳，而对于苯 - 甲苯 - 二甲苯三元组合，非竞争性抑制模型表现更好。动力学参数通过一种称为粒子群优化（PSO）的全局搜索方法进行估计。本研究的主要结果是，应用SKIP模型能够成功描述苯系物混合物复杂的生物降解动力学，其主要优势在于考虑了底物间的相互作用。
