Petersson Gunnel Hänsel, Twetman Svante
Department of Cariology, Faculty of Odontology, Malmö University, SE-205 06 Malmö, Sweden.
BMC Oral Health. 2015 Jan 27;15:17. doi: 10.1186/1472-6831-15-17.
To validate baseline caries risk classifications according to the Cariogram model with the actual caries development over a 3-year period in a group of young adults living in Sweden.
The study group consisted of 1,295 19-year-old patients that completed a comprehensive clinical baseline examination, including radiographs and salivary tests. An individual caries risk profile was computed and the patient was placed in one of five risk categories. After 3 years, 982 patients (75.8%) were re-examined and caries increment for each patient was calculated. The outcome was expressed as sensitivity, specificity and predictive values and compared with a risk assessment scheme used in Public Dental Service.
The drop-outs displayed more risk factors and a significantly higher caries burden at baseline compared with those that remained in the project (p < 0.05). There was a strong association between the Cariogram risk categories and the 3-year caries increment on cavity level but the predictive values were modest. The high or very high caries risk categories yielded high specificities (>90%) but poor sensitivities. The low risk groups displayed higher sensitivities on expense of impaired specificities. No combinations proved clinically useful values according to Yuoden's index.
Within the limitations of the present study, the computer-based Cariogram did not perform better than a caries risk assessment scheme based on past caries experience and caries progression, over a 3-year period in young adults.
根据Cariogram模型验证基线龋病风险分类,该分类基于瑞典一组年轻成年人3年期间的实际龋病发展情况。
研究组由1295名19岁患者组成,他们完成了全面的临床基线检查,包括X光片和唾液检测。计算个体龋病风险概况,并将患者分为五个风险类别之一。3年后,对982名患者(75.8%)进行复查,并计算每位患者的龋病增量。结果以敏感性、特异性和预测值表示,并与公共牙科服务中使用的风险评估方案进行比较。
与留在项目中的患者相比,退出者在基线时显示出更多的风险因素和明显更高的龋病负担(p < 0.05)。Cariogram风险类别与3年龋病增量在龋洞水平上有很强的关联,但预测值一般。高或非常高龋病风险类别具有较高的特异性(>90%),但敏感性较差。低风险组以特异性受损为代价显示出较高的敏感性。根据尤登指数,没有组合显示出临床有用的值。
在本研究的局限性内,基于计算机的Cariogram在年轻成年人3年期间的表现并不优于基于过去龋病经验和龋病进展的龋病风险评估方案。