术后延迟放疗对舌癌和口底鳞状细胞癌的局部控制作用
Delayed postoperative radiation therapy in local control of squamous cell carcinoma of the tongue and floor of the mouth.
作者信息
Amar Ali, Chedid Helma Maria, Curioni Otávio Alberto, Dedivitis Rogério Aparecido, Rapoport Abrão, Cernea Claudio Roberto, Brandão Lenine Garcia
机构信息
Hospital Heliópolis, Brazil.
Universidade de São Paulo, Brazil.
出版信息
Einstein (Sao Paulo). 2014 Oct-Dec;12(4):477-9. doi: 10.1590/S1679-45082014AO3006.
OBJECTIVE
To evaluate the effect of time between surgery and postoperative radiation therapy on local recurrence of squamous cell carcinoma of the tongue and floor of the mouth.
METHODS
A total of 154 patients treated between 1996 and 2007 were selected considering local recurrence rate and time of the adjuvant radiotherapy.
RESULTS
Local recurrence was diagnosed in 54 (35%) patients. Radiation therapy reduced the rate of local recurrences, although with no statistical significance. The time between surgery and initiation of postoperative radiotherapy did not significantly influence the risk of local recurrence in patients referred to adjuvant treatment (p=0.49).
CONCLUSION
In the presence of risk factors for local recurrence, a short delay in starting the adjuvant radiation therapy does not contraindicate its performance.
目的
评估手术与术后放疗之间的时间间隔对舌癌和口底鳞状细胞癌局部复发的影响。
方法
选取1996年至2007年间接受治疗的154例患者，考虑局部复发率和辅助放疗时间。
结果
54例（35%）患者被诊断为局部复发。放疗降低了局部复发率，尽管无统计学意义。手术与术后放疗开始之间的时间间隔对接受辅助治疗患者的局部复发风险无显著影响（p = 0.49）。
结论
存在局部复发风险因素时，辅助放疗开始的短暂延迟并不妨碍其实施。
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