Homaei-Shandiz Fatemeh, Jafarzadeh-Esfehani Reza, Moazzen Nasrin, Amirabadi Amir
Associated Professor of Radiation Oncology, Solid tumors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Medical Student, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Iran J Cancer Prev. 2014 Fall;7(4):244-7.
Inflammatory pseudotumour describes as a wide range of neoplastic and reactive lesions. One of the rare presentations of these tumors is found in the salpinx. This case report characterizes a thirty six year old woman with a history of left sided abdominal pain for a few months. Further examinations revealed that she had a complex cyst in her left salpinx. The patient had normal levels of tumor markers such as CA125, Alfa Fetoprotein (AFP), and Human Chorionic Gonadotropin (hCG), while other paraclinical test were in normal values Additionaly The patient underwent left salpingectomy by a gynecologist. The pathological diagnosis of the lesion was inflammatory myofibroblastic tumor (IMT). In immunohistochemistry the tumor stains was moderately positive in anaplastic lymphoma kinase (ALK) and also actin positive. Total resection of tumor was performed with no complications and remained disease free during follow up for 40 months. Although Inflammatory Myofibroblastic Tumor (IMT) is benign in nature, but in order to improve the prognosis, this tumor requires low intensity surgical treatment.
炎性假瘤描述的是一系列肿瘤性和反应性病变。这些肿瘤的罕见表现之一见于输卵管。本病例报告描述了一名36岁女性,有几个月的左侧腹痛病史。进一步检查发现她左侧输卵管有一个复杂囊肿。患者的肿瘤标志物如CA125、甲胎蛋白(AFP)和人绒毛膜促性腺激素(hCG)水平正常,而其他辅助检查结果也在正常范围内。此外,该患者由妇科医生进行了左侧输卵管切除术。病变的病理诊断为炎性肌纤维母细胞瘤(IMT)。免疫组织化学检查显示,肿瘤在间变性淋巴瘤激酶(ALK)染色呈中度阳性,肌动蛋白也呈阳性。肿瘤进行了完整切除,无并发症发生,在40个月的随访期间无疾病复发。尽管炎性肌纤维母细胞瘤(IMT)本质上是良性的,但为了改善预后,这种肿瘤需要低强度的手术治疗。