全甲状腺切除术后患者接受放射性碘（I-131）治疗后的唾液腺功能障碍：重点关注放射性碘治疗剂量。
Salivary gland dysfunction after radioactive iodine (I-131) therapy in patients following total thyroidectomy: emphasis on radioactive iodine therapy dose.
作者信息
Lee Han Na, An Ji Young, Lee Kyung Mi, Kim Eui Jong, Choi Woo Suk, Kim Deog Yoon
机构信息
Department of Radiology, College of Medicine, Kyung Hee University, Seoul, Korea.
Department of Radiology, College of Medicine, Kyung Hee University, Seoul, Korea.
出版信息
Clin Imaging. 2015 May-Jun;39(3):396-400. doi: 10.1016/j.clinimag.2014.12.018. Epub 2015 Jan 7.
PURPOSE
The purpose of this study was to retrospectively evaluate symptoms, images of salivary gland dysfunction, and related clinical factors in thyroid cancer patients with total thyroidectomy followed by radioiodine therapy (RIT).
METHODS
We included 164 patients who underwent thyroid ultrasonography or contrast-enhanced neck computed tomography more than 6 months later after RIT. Correlation between subjective symptoms and various RIT doses was also evaluated.
RESULTS
Swelling and decreased salivary volume were the most common symptoms and images. RIT dose was the only factor with a positive correlation (P<.001).
CONCLUSION
The dose of RIT should be carefully determined to minimize gland dysfunction.
目的
本研究的目的是回顾性评估接受甲状腺全切术并随后进行放射性碘治疗（RIT）的甲状腺癌患者的症状、唾液腺功能障碍影像及相关临床因素。
方法
我们纳入了164例在RIT后6个月以上接受甲状腺超声检查或颈部增强计算机断层扫描的患者。还评估了主观症状与各种RIT剂量之间的相关性。
结果
肿胀和唾液量减少是最常见的症状和影像表现。RIT剂量是唯一具有正相关性的因素（P<0.001）。
结论
应谨慎确定RIT剂量，以尽量减少腺体功能障碍。
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