Koch Michael, Müller Sarina, Mantsopoulos Konstantinos, Iro Heinrich, Sievert Matti
Department of Otorhinolaryngology and Head and Neck Surgery, University of Erlangen-Nuremberg, 91054 Erlangen, Germany.
J Clin Med. 2024 Jan 23;13(3):657. doi: 10.3390/jcm13030657.
To assess the correlation/association between ultrasound and sialendoscopy findings in radioactive iodine therapy-induced sialadenitis (RAIS).
Patients presenting with RAIS were investigated with ultrasound and sialendoscopy. Four pathologic ultrasound parameters and seven pathologic sialendoscopy parameters were retrospectively assessed. Correlations/associations between ultrasound and sialendoscopy findings and associations between the changes between the first and last ultrasound and sialendoscopy findings were assessed separately for the parotid (PG) and submandibular glands (SMG).
Sixty-seven patients were included. In the first examination, 107 glands were investigated (PGs 88.8%, SMGs 11.21%), and in the last examination, 64 glands were investigated (90.6% PGs, 9.4% SMGs). Highly significant positive associations were observed between the severity or category of ultrasound and sialendoscopy findings for first and last examinations for PGs (both = 0.0001) and SMGs ( = 0.002; = 0.037). Duct dilation had a significant negative association with the sialendoscopy findings for PGs in the first and last examinations (both = 0.0001), but not for SMGs. Comparison of changes in the ultrasound and sialendoscopy findings between the first and last examinations showed a significant positive association for PGs ( = 0.0001) but not for SMGs.
Ultrasound and sialendoscopy findings for the parenchyma and duct system in RAIS showed significant associations/correlations and can be useful for effective management in RAIS.
评估放射性碘治疗所致涎腺炎（RAIS）中超声与唾液腺内镜检查结果之间的相关性。
对患有RAIS的患者进行超声和唾液腺内镜检查。回顾性评估四个超声病理参数和七个唾液腺内镜病理参数。分别对腮腺（PG）和下颌下腺（SMG）评估超声与唾液腺内镜检查结果之间的相关性以及首次和末次超声与唾液腺内镜检查结果变化之间的相关性。
纳入67例患者。首次检查时，共检查了107个腺体（腮腺占88.8%，下颌下腺占11.21%），末次检查时，共检查了64个腺体（腮腺占90.6%，下颌下腺占9.4%）。对于腮腺和下颌下腺，首次和末次检查的超声与唾液腺内镜检查结果的严重程度或类别之间均观察到高度显著的正相关（腮腺均为P = 0.0001，下颌下腺P = 0.002；P = 0.037）。导管扩张与腮腺首次和末次检查的唾液腺内镜检查结果呈显著负相关（均为P = 0.0001），但与下颌下腺无关。首次和末次检查之间超声与唾液腺内镜检查结果变化的比较显示，腮腺有显著正相关（P = 0.0001），而下颌下腺无显著正相关。
RAIS实质和导管系统的超声与唾液腺内镜检查结果显示出显著的相关性，可用于RAIS的有效管理。
