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[皮肤肿瘤学的现代诊断程序]

[Modern diagnostic procedures in dermatological oncology].

作者信息

Kellner C, Reinhold U

机构信息

Dermatologisches Zentrum Bonn, Friedensplatz, Friedensplatz 16, 53111, Bonn, Deutschland,

出版信息

Pathologe. 2015 Feb;36(1):11-5. doi: 10.1007/s00292-014-2062-4.

DOI:10.1007/s00292-014-2062-4
PMID:25630484
Abstract

BACKGROUND

New technologies, such as confocal laser scanning microscopy (CLSM), optical coherence tomography (OCT), electrical impedance spectroscopy (EIS) and multispectral analysis have greatly enriched the possibilities of diagnostics in dermatological oncology. They can be supplementary tools to dermatoscopy and histopathology to make a more precise diagnosis of skin lesions.

OBJECTIVES

Increasing relevance of new systems for diagnosis and monitoring of dermatological therapy. Presentation of the technology and the diagnostic range of application for various skin lesions.

MATERIAL AND METHODS

Presentation of scientifically relevant studies and statistical data, discussion of basic research and expert recommendations.

RESULTS

The diagnostic spectrum of dermatological oncology has been significantly enriched in recent years. New technologies, such as CLSM, OCT, EIS and multispectral analysis are non-invasive and therefore painless for the patient. In only a few minutes these techniques deliver valid data and findings and provide dermatologists with more accurate diagnostic information about benign or malignant melanocytic skin lesions or the various forms of white skin cancer.

CONCLUSION

In recent years, non-invasive diagnostic and analytical imaging procedures have been progressively established in dermatological oncology and supplement classical dermatoscopy and histopathology. With respect to the follow-up of different therapeutic modalities unnecessary tissue biopsies and scars can be reduced for patients.

摘要

背景

共聚焦激光扫描显微镜(CLSM)、光学相干断层扫描(OCT)、电阻抗光谱(EIS)和多光谱分析等新技术极大地丰富了皮肤肿瘤学诊断的可能性。它们可以作为皮肤镜检查和组织病理学的辅助工具,以便对皮肤病变做出更精确的诊断。

目的

提高新系统在皮肤疾病诊断和治疗监测中的相关性。介绍该技术及其在各种皮肤病变中的诊断应用范围。

材料与方法

介绍科学相关研究和统计数据,讨论基础研究并给出专家建议。

结果

近年来,皮肤肿瘤学的诊断范围得到了显著扩展。CLSM、OCT、EIS和多光谱分析等新技术是非侵入性的,因此对患者来说无痛。这些技术只需几分钟就能提供有效的数据和结果,并为皮肤科医生提供有关良性或恶性黑素细胞性皮肤病变或各种形式的白色皮肤癌的更准确诊断信息。

结论

近年来,非侵入性诊断和分析成像程序已逐渐在皮肤肿瘤学中确立,并补充了传统的皮肤镜检查和组织病理学。对于不同治疗方式的随访,可为患者减少不必要的组织活检和疤痕。

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