Changing cerebral blood flow in normal pressure hydrocephalus after the tap test can predict clinical improvement.
作者信息
Sedighi Behnaz, Shafiee Kaveh, Seifaldini Rostam, Abdi As'ad
机构信息
Department of Neurology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Department of Neurology, School of Medicine, Neurology Research Center, Kerman University of Medical Sciences, Kerman, Iran.
出版信息
Iran J Neurol. 2014 Oct 6;13(4):245-9.
BACKGROUND
We studied the role of cerebrospinal fluid (CSF) tap test at idiopathic normal pressure hydrocephalus (INPH) in improving cerebral blood flow velocity indices by transcranial Doppler (TCD) sonography.
METHODS
Twelve patients with assumed INPH were included in the study. The CSF tap test and INPH grading score was carried out according to the standard protocol. TCD was performed before and after the tap test for assessing blood flow in middle cerebral and anterior cerebral arteries.
RESULTS
Five INPH patients (41.7%) had clinical improvement as defined by at least one point reduction in INPH grading scale. The baseline TCD parameters of the middle cerebral artery were significantly higher compared with the control, and those parameters were decreased after tap test in those who improved.
CONCLUSION
Our study showed that improvement in INPH grading score after CSF tap test might correlate with changing in TCD parameter in MCA and TCD parameter might be useful for shunt response in these patients.
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