Kushner M, Younkin D, Weinberger J, Hurtig H, Goldberg H, Reivich M
Neurology. 1984 Jan;34(1):96-9. doi: 10.1212/wnl.34.1.96.
We studied the effect of CSF drainage on cerebral blood flow (CBF) in normal pressure hydrocephalus (NPH) and non-NPH dementia using the 133Xenon inhalation technique. Dementia patients had lower CBF than matched elderly normals. Flow values for NPH and non-NPH patients did not differ before or after CSF drainage. CBF did not increase after lumbar puncture, and these measurements were not useful in predicting the outcome of ventricular shunt surgery. Postoperative CBF did not increase after successful shunting.
我们使用氙-133吸入技术研究了脑脊液引流对正常压力脑积水（NPH）和非NPH痴呆患者脑血流量（CBF）的影响。痴呆患者的脑血流量低于匹配的老年正常人群。脑脊液引流前后，NPH患者和非NPH患者的血流值无差异。腰椎穿刺后脑血流量未增加，这些测量结果对预测脑室分流手术的结果并无帮助。成功分流术后脑血流量也未增加。
