Acta Med Indones. 2014 Oct;46(4):348-59.
Pandemic obesity and diabetes mellitus (DM), particularly type-2 DM (T2DM) now has become a serious threat for people worldwide. The International Diabetes Federation (IDF) suggests that the prevalence of DM in the world is 1.9% and it has made DM as the 7th leading cause of death worldwide. It has been estimated that the prevalence of diabetes between 1994 and 2010 was projected as much as 215.6 milion people; however an evaluation in 2007 revealed that the number of diabetic patients has reached 246 million people and it has been concerned that the number would increase in 2025 reaching more than 300 million people. Patients with DM may have various complilcations, including macrovascular diseases (heart disease, stroke and peripheral vascular disease) and microvascular diseases (retinopathy, neuropathy and nephropathy). Complications of DM have started early before the diagnosis of DM has been made. About 50% of patients have alreadly had one chronic complication at the time of diagnosis. Therefore, it is necessary to have a guideline on management of prediabetes condition associated with prevention of chonic complication and cardiovascular risk of diabetes. The guideline is expected to improve the skills of health care professionals in recognizing prediabetes condition, identifying people at high risk for diabetes and providing an appropriate management so that the incidence and complication of DM can be reduced.
肥胖症和糖尿病大流行,尤其是2型糖尿病(T2DM),如今已成为全球人民面临的严重威胁。国际糖尿病联合会(IDF)指出,全球糖尿病患病率为1.9%,糖尿病已成为全球第七大死因。据估计,1994年至2010年期间糖尿病患病率预计高达2.156亿人;然而,2007年的一项评估显示,糖尿病患者人数已达2.46亿人,人们担心到2025年这一数字将增至3亿多人以上。糖尿病患者可能会出现各种并发症,包括大血管疾病(心脏病、中风和外周血管疾病)和微血管疾病(视网膜病变、神经病变和肾病)。糖尿病并发症在糖尿病确诊之前就已开始出现。约50%的患者在确诊时已患有一种慢性并发症。因此,有必要制定一项关于糖尿病前期管理的指南,以预防糖尿病的慢性并发症和心血管风险。该指南有望提高医护人员识别糖尿病前期状况、确定糖尿病高危人群以及提供适当管理的技能,从而降低糖尿病的发病率和并发症。