Hale A S, Sandler M, Hannah P, Bridges P K
Department of Psychiatry, United Medical School, St Thomas' Hospital, London.
Lancet. 1989 Feb 4;1(8632):234-6. doi: 10.1016/s0140-6736(89)91255-5.
In a group of 30 patients with major unipolar depressive disorder urinary excretion of tyramine sulphate was measured after an oral dose of tyramine. There was a significant correlation between impaired tyramine conjugation and response to tricyclic antidepressant medication.
在一组30例重度单相抑郁症患者中,口服酪胺后测定了硫酸酪胺的尿排泄量。酪胺结合受损与三环类抗抑郁药治疗反应之间存在显著相关性。