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家族性主动脉缩窄:老年人难治性高血压的罕见病因:一例报告

Familial aortic coarctation: a rare cause of refractory hypertension in the elderly: a case report.

作者信息

Lara-Rojas Carmen M, Bernal-Lopez M Rosa, Lopez-Carmona M Dolores, Gomez-Huelgas Ricardo

机构信息

From the Internal Medicine Department, Biomedical Institute of Malaga (IBIMA), Regional University Hospital of Malaga, Spain (CML-R, MDL-C, G-H); Ciber Fisiopatología de la Obesidad y Nutrición (CB06/003) Instituto de Salud Carlos III, Madrid, Spain (MRB-L, RG-H); and Biomedical Research Laboratory, Internal Medicine Department, Biomedical Institute of Malaga (IBIMA), Regional University Hospital of Malaga, Spain (MRB-L).

出版信息

Medicine (Baltimore). 2015 Jan;94(4):e467. doi: 10.1097/MD.0000000000000467.

DOI:10.1097/MD.0000000000000467
PMID:25634191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4602944/
Abstract

We report the first case of late presentation of familial aortic coarctation, a rare cause of hypertension. Diagnosis of familial aortic coarctation in the elderly is exceptional, given that in the absence of endovascular or surgical repair patients do not usually survive beyond 50 years of age. Our case concerns a 72-year-old woman with hypertension of long evolution, control of which improved markedly after endovascular repair of the coarctation. Her son had undergone surgery for repair of aortic coarctation at the age of 23 years.

摘要

我们报告了首例家族性主动脉缩窄的迟发性病例,这是一种罕见的高血压病因。鉴于在没有血管内或手术修复的情况下,患者通常活不过50岁,所以老年患者中诊断出家族性主动脉缩窄的情况极为罕见。我们的病例是一位患有长期高血压的72岁女性,在对缩窄进行血管内修复后,血压控制得到了显著改善。她的儿子在23岁时接受了主动脉缩窄修复手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6f/4602944/726cf5031932/medi-94-e467-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6f/4602944/726cf5031932/medi-94-e467-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6f/4602944/726cf5031932/medi-94-e467-g001.jpg

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本文引用的文献

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2
Prenatal diagnosis of de novo partial trisomy 18p and partial monosomy 18q recurrent in a family with fatal aortic coarctation.先证者为新发部分 18p 三体和部分 18q 单体,家族中存在致死性主动脉缩窄的病例。
Gene. 2013 Mar 15;517(1):132-6. doi: 10.1016/j.gene.2012.12.001. Epub 2012 Dec 8.
3
Multiple regions of coarctation of the aorta associated with bicuspid aortic valve in a 74-year-old female.
一名74岁女性患者存在多处主动脉缩窄区域,并伴有二叶式主动脉瓣。
Eur Heart J Cardiovasc Imaging. 2012 Jun;13(6):531. doi: 10.1093/ehjci/jes006. Epub 2012 Jan 26.
4
Internal mammary artery dilatation in a patient with aortic coarctation, aortic stenosis, and coronary disease. Case report.一名患有主动脉缩窄、主动脉狭窄和冠心病患者的乳内动脉扩张。病例报告。
J Cardiothorac Surg. 2011 Apr 17;6:55. doi: 10.1186/1749-8090-6-55.
5
Familial pseudocoarctation of the aorta.
Pediatr Cardiol. 2011 Jun;32(5):692-5. doi: 10.1007/s00246-011-9933-8. Epub 2011 Feb 25.
6
ESC Guidelines for the management of grown-up congenital heart disease (new version 2010).欧洲心脏病学会成人先天性心脏病管理指南(2010年新版)
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