Zhao Yuanyuan, Chen Xuemei
Department of Botany and Plant Sciences, Institute of Integrative Genome Biology, University of California, Riverside, CA 92521.
Department of Botany and Plant Sciences, Institute of Integrative Genome Biology, University of California, Riverside, CA 92521 ; Howard Hughes Medical Institute, University of California, Riverside, CA 92521.
Natl Sci Rev. 2014 Jun;1(2):219-229. doi: 10.1093/nsr/nwu003.
Cytosine DNA methylation is an epigenetic modification in eukaryotes that maintains genome integrity and regulates gene expression. The DNA methylation patterns in plants are more complex than those in animals, and plants and animals have common as well as distinct pathways in regulating DNA methylation. Recent studies involving genetic, molecular, biochemical and genomic approaches have greatly expanded our knowledge of DNA methylation in plants. The roles of many proteins as well as non-coding RNAs in DNA methylation have been uncovered.
胞嘧啶DNA甲基化是真核生物中的一种表观遗传修饰，可维持基因组完整性并调节基因表达。植物中的DNA甲基化模式比动物中的更为复杂，并且植物和动物在调节DNA甲基化方面既有共同的途径，也有不同的途径。最近涉及遗传学、分子生物学、生物化学和基因组学方法的研究极大地扩展了我们对植物DNA甲基化的认识。许多蛋白质以及非编码RNA在DNA甲基化中的作用已被揭示。
